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24 results for eIF-2+Kinase+-+deficiency

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The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage
Author / Creator:Lin, Wensheng ; Bailey, Samantha L ; Ho, Hanson ; Harding, Heather P ; Ron, David ; Miller, Stephen D ; Popko, Brian
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2007-02, Vol.117 (2), p.448-456
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Novel role of PKR in inflammasome activation and HMGB1 release
Author / Creator:Lu, Ben ; Nakamura, Takahisa ; Inouye, Karen ; Li, Jianhua ; Tang, Yiting ; Lundbäck, Peter ; Valdes-Ferrer, Sergio I. ; Olofsson, Peder S. ; Kalb, Thomas ; Roth, Jesse ; Zou, Yongrui ; Erlandsson-Harris, Helena ; Yang, Huan ; Ting, Jenny P.-Y. ; Wang, Haichao ; Andersson, Ulf ; Antoine, Daniel J. ; Chavan, Sangeeta S. ; Hotamisligil, Gökhan S. ; Tracey, Kevin J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-08, Vol.488 (7413), p.670-674
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Inhibition of the unfolded protein response reduces arrhythmia risk after myocardial infarction
Author / Creator:Liu, Man ; Liu, Hong ; Parthiban, Preethy ; Kang, Gyeoung-Jin ; Shi, Guangbin ; Feng, Feng ; Zhou, Anyu ; Gu, Lianzhi ; Karnopp, Courtney ; Tolkacheva, Elena G ; Dudley, Jr, Samuel C
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-09, Vol.131 (18), p.1-9
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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells
Author / Creator:Bedard, Melissa ; Shrestha, Dilip ; Priestman, David A. ; Wang, Yuting ; Schneider, Falk ; Matute, Juan D. ; Iyer, Shankar S. ; Gileadi, Uzi ; Prota, Gennaro ; Kandasamy, Matheswaran ; Veerapen, Natacha ; Besra, Gurdyal ; Fritzsche, Marco ; Zeissig, Sebastian ; Shevchenko, Andrej ; Christianson, John C. ; Platt, Frances M. ; Eggeling, Christian ; Blumberg, Richard S. ; Salio, Mariolina ; Cerundolo, Vincenzo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (47), p.23671-23681
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PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
Author / Creator:Bobrovnikova-Marjon, E ; Grigoriadou, C ; Pytel, D ; Zhang, F ; Ye, J ; Koumenis, C ; Cavener, D ; Diehl, J A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2010-07, Vol.29 (27), p.3881-3895
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PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions
Author / Creator:Tible, Marion ; Mouton Liger, François ; Schmitt, Julien ; Giralt, Albert ; Farid, Karim ; Thomasseau, Sylvie ; Gourmaud, Sarah ; Paquet, Claire ; Rondi Reig, Laure ; Meurs, Eliane ; Girault, Jean‐Antoine ; Hugon, Jacques
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-06, Vol.18 (3), p.e12887-n/a
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PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway
Author / Creator:GUPTA, Sounak ; MCGRATH, Barbara ; CAVENER, Douglas R
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2010-08, Vol.59 (8), p.1937-1947
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Role of ER stress response in photodynamic therapy: ROS generated in different subcellular compartments trigger diverse cell death pathways
Author / Creator:Moserova, Irena ; Kralova, Jarmila
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e32972-e32972
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PERK-mediated translational control is required for collagen secretion in chondrocytes
Author / Creator:Hisanaga, Satoshi ; Miyake, Masato ; Taniuchi, Shusuke ; Oyadomari, Miho ; Morimoto, Masatoshi ; Sato, Ryosuke ; Hirose, Jun ; Mizuta, Hiroshi ; Oyadomari, Seiichi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-01, Vol.8 (1), p.773-13, Article 773
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PKR modulates abnormal brain signaling in experimental obesity
Author / Creator:Taga, Mariko ; Mouton-Liger, François ; Sadoune, Malha ; Gourmaud, Sarah ; Norman, Jenny ; Tible, Marion ; Thomasseau, Sylvie ; Paquet, Claire ; Nicoll, James A R ; Boche, Delphine ; Hugon, Jacques
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-05, Vol.13 (5), p.e0196983-e0196983
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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
Author / Creator:Hsu, Li-Chung ; Mo Park, Jin ; Zhang, Kezhong ; Luo, Jun-Li ; Maeda, Shin ; Kaufman, Randal J. ; Eckmann, Lars ; Guiney, Donald G. ; Karin, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2004-03, Vol.428 (6980), p.341-345
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Hyperthermia induces the ER stress pathway
Author / Creator:Xu, Xu ; Gupta, Sounak ; Hu, Wenli ; McGrath, Barbara C ; Cavener, Douglas R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23740-e23740
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PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model
Author / Creator:Mouton-Liger, F ; Rebillat, A-S ; Gourmaud, S ; Paquet, C ; Leguen, A ; Dumurgier, J ; Bernadelli, P ; Taupin, V ; Pradier, L ; Rooney, T ; Hugon, J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2015-01, Vol.6 (1), p.e1594-e1594
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Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R
Author / Creator:Wu, Kangyun ; Koo, Jovanka ; Jiang, Xiuju ; Chen, Ran ; Cohen, Stanley N ; Nathan, Carl
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e30512-e30512
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Deficient PKR in RAX/PKR Association Ameliorates Ethanol-Induced Neurotoxicity in the Developing Cerebellum
Author / Creator:Li, Hui ; Chen, Jian ; Qi, Yuanlin ; Dai, Lu ; Zhang, Mingfang ; Frank, Jacqueline A. ; Handshoe, Jonathan W. ; Cui, Jiajun ; Xu, Wenhua ; Chen, Gang
Publisher:New York: Springer US
Journal title:Cerebellum (London, England), 2015-08, Vol.14 (4), p.386-397
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Specific Phenotypic Restoration of an Attenuated Virus by Knockout of a Host Resistance Gene
Author / Creator:Leib, David A. ; Machalek, Michael A. ; Bryan R. G. Williams ; Silverman, Robert H. ; Virgin, Herbert W.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (11), p.6097-6101
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Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR
Author / Creator:Pataer, Abujiang ; Vorburger, Stephan A. ; Chada, Sunil ; Balachandran, Siddharth ; Barber, Glen N. ; Roth, Jack A. ; Hunt, Kelly K. ; Swisher, Stephen G.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2005-05, Vol.11 (5), p.717-723
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Double-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infection
Author / Creator:Minor, Radiah A Corn ; Limmon, Gino V ; Miller-DeGraff, Laura ; Dixon, Darlene ; Andrews, Danica M K ; Kaufman, Randal J ; Imani, Farhad
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Journal of interferon & cytokine research, 2010-04, Vol.30 (4), p.263-272
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Potential role of PKR in double-stranded RNA-induced macrophage activation
Author / Creator:Maggi Jr, Leonard B. ; Heitmeier, Monique R. ; Scheuner, Donalyn ; Kaufman, Randal J. ; Buller, R.Mark L. ; Corbett, John A.
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2000-07, Vol.19 (14), p.3630-3638
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Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to defi...
Author / Creator:Khabar, K S ; Dhalla, M ; Siddiqui, Y ; Zhou, A ; Al-Ahdal, M N ; Der, S D ; Silverman, R H ; Williams, B R
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Journal of interferon & cytokine research, 2000-07, Vol.20 (7), p.653-659
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The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

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Novel role of PKR in inflammasome activation and HMGB1 release

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Inhibition of the unfolded protein response reduces arrhythmia risk after myocardial infarction

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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells

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PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

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PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions

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PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

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Role of ER stress response in photodynamic therapy: ROS generated in different subcellular compartments trigger diverse cell death pathways

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PERK-mediated translational control is required for collagen secretion in chondrocytes

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PKR modulates abnormal brain signaling in experimental obesity

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

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Hyperthermia induces the ER stress pathway

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PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model

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Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R

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Deficient PKR in RAX/PKR Association Ameliorates Ethanol-Induced Neurotoxicity in the Developing Cerebellum

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Specific Phenotypic Restoration of an Attenuated Virus by Knockout of a Host Resistance Gene

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Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR

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Double-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infection

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Potential role of PKR in double-stranded RNA-induced macrophage activation

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Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to defi...

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