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Loss-of-Function Ferrochelatase and Gain-of-Function Erythroid-Specific 5-Aminolevulinate Synthase Mutations Causing Erythropoietic Protoporphyria and X-Linked Protoporphyria in North American Patient...
Author / Creator:Balwani, Manisha ; Doheny, Dana ; Bishop, David F. ; Nazarenko, Irina ; Yasuda, Makiko ; Dailey, Harry A. ; Anderson, Karl E. ; Bissell, D. Montgomery ; Bloomer, Joseph ; Bonkovsky, Herbert L. ; Phillips, John D. ; Liu, Lawrence ; Desnick, Robert J.
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2013-01, Vol.19 (1), p.26-29
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Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria
Author / Creator:Dickey, Amy K. ; Quick, Corbin ; Ducamp, Sarah ; Zhu, Zhaozhong ; Feng, Yen-Chen A. ; Naik, Hetanshi ; Balwani, Manisha ; Anderson, Karl E. ; Lin, Xihong ; Phillips, John E. ; Rebeiz, Lina ; Bonkovsky, Herbert L. ; McGuire, Brendan M. ; Wang, Bruce ; Chasman, Daniel I. ; Smoller, Jordan W. ; Fleming, Mark D. ; Christiani, David C.
Publisher:New York: Elsevier Inc
Journal title:Genetics in medicine, 2021-01, Vol.23 (1), p.140-148
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5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
Author / Creator:Howley, Richard ; Chandratre, Sharayu ; Chen, Bin
Publisher:Switzerland: MDPI AG
Journal title:Bioengineering (Basel), 2023-04, Vol.10 (4), p.496
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Molecular Expression and Characterization of Erythroid-Specific 5-Aminolevulinate Synthase Gain-of-Function Mutations Causing X-Linked Protoporphyria
Author / Creator:Bishop, David F. ; Tchaikovskii, Vassili ; Nazarenko, Irina ; Desnick, Robert J.
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2013-01, Vol.19 (1), p.18-25
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CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening
Author / Creator:Wijerathna, Hitihami M. S. M. ; Shanaka, Kateepe A. S. N. ; Raguvaran, Sarithaa S. ; Jayamali, Bulumulle P. M. V. ; Kim, Seok-Hyung ; Kim, Myoung-Jin ; Jung, Sumi ; Lee, Jehee
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-10, Vol.25 (19), p.10819
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MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axes
Author / Creator:Chelakkot, Vipin Shankar ; Liu, Kaiwen ; Yoshioka, Ema ; Saha, Shaykat ; Xu, Danyang ; Licursi, Maria ; Dorward, Ann ; Hirasawa, Kensuke
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.22124-22124, Article 22124
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Ferrochelatase is a therapeutic target for ocular neovascularization
Author / Creator:Basavarajappa, Halesha D ; Sulaiman, Rania S ; Qi, Xiaoping ; Shetty, Trupti ; Sheik Pran Babu, Sardar ; Sishtla, Kamakshi L ; Lee, Bit ; Quigley, Judith ; Alkhairy, Sameerah ; Briggs, Christian M ; Gupta, Kamna ; Tang, Buyun ; Shadmand, Mehdi ; Grant, Maria B ; Boulton, Michael E ; Seo, Seung‐Yong ; Corson, Timothy W
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2017-06, Vol.9 (6), p.786-801
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Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy
Author / Creator:Teng, L ; Nakada, M ; Zhao, S-G ; Endo, Y ; Furuyama, N ; Nambu, E ; Pyko, I V ; Hayashi, Y ; Hamada, J-I
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2011-03, Vol.104 (5), p.798-807
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The penetrance of dominant erythropoietic protoporphyria is modulated by expression of wildtype FECH
Author / Creator:Gouya, Laurent ; Puy, Herve ; Robreau, Anne-Marie ; Bourgeois, Monique ; Lamoril, Jerôme ; Da Silva, Vasco ; Grandchamp, Bernard ; Deybach, Jean-Charles
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2002-01, Vol.30 (1), p.27-28
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Identification of FECH gene multiple variations in two Chinese patients with erythropoietic protoporphyria and a review
Author / Creator:Long, Zhang-biao ; Wang, Yong-wei ; Yang, Chen ; Liu, Gang ; Du, Ya-li ; Nie, Guang-jun ; Chang, Yan-zhong ; Han, Bing
Publisher:Hangzhou: Zhejiang University Press
Journal title:Journal of Zhejiang University. B. Science, 2016-10, Vol.17 (10), p.813-820
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Inhibition of ferrochelatase impairs vascular eNOS/NO and sGC/cGMP signaling
Author / Creator:Zhang, Bin ; Alruwaili, Norah ; Kandhi, Sharath ; Deng, Wensheng ; Huang, An ; Wolin, Michael S. ; Sun, Dong
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-07, Vol.13 (7), p.e0200307-e0200307
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Functional Assignments for the Carboxyl-Terminal Domains of the Ferrochelatase from Synechocystis PCC 6803: The CAB Domain Plays a Regulatory Role, and Region II Is Essential for Catalysis
Author / Creator:Sobotka, Roman ; Tichy, Martin ; Wilde, Annegret ; Hunter, C. Neil
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2011-04, Vol.155 (4), p.1735-1747
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Impact of Phosphorylation at Various Sites on the Active Pocket of Human Ferrochelatase: Insights from Molecular Dynamics Simulations
Author / Creator:Guo, Mingshan ; Lin, Yuhong ; Obi, Chibuike David ; Zhao, Peng ; Dailey, Harry A. ; Medlock, Amy E. ; Shen, Yong
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-06, Vol.25 (12), p.6360
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Gene Dosage Analysis Identifies Large Deletions of the FECH Gene in 10% of Families with Erythropoietic Protoporphyria
Author / Creator:Whatley, Sharon D. ; Mason, Nicola G. ; Alexander Holme, S. ; Anstey, Alex V. ; Elder, George H. ; Badminton, Michael N.
Publisher:Danvers, MA: Elsevier Inc
Journal title:Journal of investigative dermatology, 2007-12, Vol.127 (12), p.2790-2794
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Modelling the ferrochelatase c.315-48C modifier mutation for erythropoietic protoporphyria (EPP) in mice
Author / Creator:Barman-Aksözen, Jasmin ; Ćwiek, Paulina ; Bansode, Vijay B. ; Koentgen, Frank ; Trüb, Judith ; Pelczar, Pawel ; Cinelli, Paolo ; Schneider-Yin, Xiaoye ; Schümperli, Daniel ; Minder, Elisabeth I.
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2017-03, Vol.10 (3), p.225-233
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Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts
Author / Creator:Shah, Dhvanit I. ; Takahashi-Makise, Naoko ; Cooney, Jeffrey D. ; Li, Liangtao ; Schultz, Iman J. ; Pierce, Eric L. ; Narla, Anupama ; Seguin, Alexandra ; Hattangadi, Shilpa M. ; Medlock, Amy E. ; Langer, Nathaniel B. ; Dailey, Tamara A. ; Hurst, Slater N. ; Faccenda, Danilo ; Wiwczar, Jessica M. ; Heggers, Spencer K. ; Vogin, Guillaume ; Chen, Wen ; Chen, Caiyong ; Campagna, Dean R. ; Brugnara, Carlo ; Zhou, Yi ; Ebert, Benjamin L. ; Danial, Nika N. ; Fleming, Mark D. ; Ward, Diane M. ; Campanella, Michelangelo ; Dailey, Harry A. ; Kaplan, Jerry ; Paw, Barry H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-11, Vol.491 (7425), p.608-612
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A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease
Author / Creator:Farrag, M. S. ; Kučerová, J. ; Šlachtová, L. ; Šeda, O. ; Šperl, J. ; Martásek, Pavel
Publisher:Czech Republic: Charles University in Prague, First Faculty of Medicine
Journal title:Folia biologica, 2015-01, Vol.61 (6), p.227-232
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Proteomic Analysis of Ferrochelatase Interactome in Erythroid and Non-Erythroid Cells
Author / Creator:Obi, Chibuike David ; Dailey, Harry A. ; Jami-Alahmadi, Yasaman ; Wohlschlegel, James A. ; Medlock, Amy E.
Publisher:Switzerland: MDPI AG
Journal title:Life (Basel, Switzerland), 2023-02, Vol.13 (2), p.577
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FECH Expression Correlates with the Prognosis and Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
Author / Creator:Zhong, Guanghui ; Li, Qing ; Luo, Yang ; Liu, Yufeng ; Liu, Dawei ; li, Bin ; Wang, Tao
Publisher:New York: Hindawi
Journal title:Journal of oncology, 2022-08, Vol.2022, p.1-17
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Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation
Author / Creator:Ershov, Pavel V. ; Veselovsky, Alexander V. ; Mezentsev, Yuri V. ; Yablokov, Evgeniy O. ; Kaluzhskiy, Leonid A. ; Tumilovich, Anastasiya M. ; Kavaleuski, Anton A. ; Gilep, Andrei A. ; Moskovkina, Taisiya V. ; Medvedev, Alexei E. ; Ivanov, Alexis S.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (20), p.7605
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Loss-of-Function Ferrochelatase and Gain-of-Function Erythroid-Specific 5-Aminolevulinate Synthase Mutations Causing Erythropoietic Protoporphyria and X-Linked Protoporphyria in North American Patient...

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Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria

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5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy

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Molecular Expression and Characterization of Erythroid-Specific 5-Aminolevulinate Synthase Gain-of-Function Mutations Causing X-Linked Protoporphyria

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CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening

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MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axes

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Ferrochelatase is a therapeutic target for ocular neovascularization

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Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy

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The penetrance of dominant erythropoietic protoporphyria is modulated by expression of wildtype FECH

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Identification of FECH gene multiple variations in two Chinese patients with erythropoietic protoporphyria and a review

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Inhibition of ferrochelatase impairs vascular eNOS/NO and sGC/cGMP signaling

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Functional Assignments for the Carboxyl-Terminal Domains of the Ferrochelatase from Synechocystis PCC 6803: The CAB Domain Plays a Regulatory Role, and Region II Is Essential for Catalysis

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Impact of Phosphorylation at Various Sites on the Active Pocket of Human Ferrochelatase: Insights from Molecular Dynamics Simulations

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Gene Dosage Analysis Identifies Large Deletions of the FECH Gene in 10% of Families with Erythropoietic Protoporphyria

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Modelling the ferrochelatase c.315-48C modifier mutation for erythropoietic protoporphyria (EPP) in mice

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Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts

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A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease

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Proteomic Analysis of Ferrochelatase Interactome in Erythroid and Non-Erythroid Cells

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FECH Expression Correlates with the Prognosis and Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma

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Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation

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