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929 results for glutaminolysis

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ArticlesPeer ReviewedFull Text
Glutaminolysis as a target for cancer therapy
Author / Creator:Jin, L ; Alesi, G N ; Kang, S
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2016-07, Vol.35 (28), p.3619-3625
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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
Author / Creator:Romero, Rodrigo ; Sayin, Volkan I ; Davidson, Shawn M ; Bauer, Matthew R ; Singh, Simranjit X ; LeBoeuf, Sarah E ; Karakousi, Triantafyllia R ; Ellis, Donald C ; Bhutkar, Arjun ; Sánchez-Rivera, Francisco J ; Subbaraj, Lakshmipriya ; Martinez, Britney ; Bronson, Roderick T ; Prigge, Justin R ; Schmidt, Edward E ; Thomas, Craig J ; Goparaju, Chandra ; Davies, Angela ; Dolgalev, Igor ; Heguy, Adriana ; Allaj, Viola ; Poirier, John T ; Moreira, Andre L ; Rudin, Charles M ; Pass, Harvey I ; Vander Heiden, Matthew G ; Jacks, Tyler ; Papagiannakopoulos, Thales
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-11, Vol.23 (11), p.1362-1368
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Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate–mediated mTOR Activation and Proline Hydroxylation
Author / Creator:Ge, Jing ; Cui, Huachun ; Xie, Na ; Banerjee, Sami ; Guo, Sijia ; Dubey, Shubham ; Barnes, Stephen ; Liu, Gang
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2018-03, Vol.58 (3), p.378-390
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GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis
Author / Creator:Xia, Xichun ; Cao, Guangchao ; Sun, Guodong ; Zhu, Leqing ; Tian, Yixia ; Song, Yueqi ; Guo, Chengbin ; Wang, Xiao ; Zhong, Jingxiang ; Zhou, Wei ; Li, Peng ; Zhang, Hua ; Hao, Jianlei ; Li, Zhizhong ; Deng, Liehua ; Yin, Zhinan ; Gao, Yunfei
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-10, Vol.130 (10), p.5180-5196
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Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
Author / Creator:Bertero, Thomas ; Oldham, William M. ; Cottrill, Katherine A. ; Pisano, Sabrina ; Vanderpool, Rebecca R. ; Yu, Qiujun ; Zhao, Jingsi ; Tai, Yiyin ; Tang, Ying ; Zhang, Ying-Yi ; Rehman, Sofiya ; Sugahara, Masataka ; Qi, Zhi ; Gorcsan, John ; Vargas, Sara O. ; Saggar, Rajan ; Saggar, Rajeev ; Wallace, W. Dean ; Ross, David J. ; Haley, Kathleen J. ; Waxman, Aaron B. ; Parikh, Victoria N. ; De Marco, Teresa ; Hsue, Priscilla Y. ; Morris, Alison ; Simon, Marc A. ; Norris, Karen A. ; Gaggioli, Cedric ; Loscalzo, Joseph ; Fessel, Joshua ; Chan, Stephen Y.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3313-3335
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Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner
Author / Creator:Yun-Qian, Wang ; Hao-Lian, Wang ; Xu, Jie ; Tan, Juan ; Lin-Na, Fu ; Ji-Lin, Wang ; Tian-Hui, Zou ; Dan-Feng, Sun ; Qin-Yan, Gao ; Ying-Xuan, Chen ; Jing-Yuan, Fang
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-02, Vol.9, p.1-15
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Targeting ATF4-dependent pro-survival autophagy to synergize glutaminolysis inhibition
Author / Creator:Han, Shuting ; Zhu, Liyuan ; Zhu, Yiran ; Meng, Yuan ; Li, Jiaqiu ; Song, Ping ; Yousafzai, Neelum Aziz ; Feng, Lifeng ; Chen, Miaoqin ; Wang, Yanmei ; Jin, Hongchuan ; Wang, Xian
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2021-01, Vol.11 (17), p.8464-8479
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fMiRNA-192 and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma
Author / Creator:Ge, Yunxia ; Yan, Xiaodan ; Jin, Yiguang ; Yang, Xinyu ; Yu, Xiang ; Zhou, Liqing ; Han, Sichong ; Yuan, Qipeng ; Yang, Ming
Publisher:San Francisco, CA USA: Public Library of Science
Journal title:PLoS genetics, 2015-12, Vol.11 (12), p.e1005726
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Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
Author / Creator:Aurora, Arin B. ; Khivansara, Vishal ; Leach, Ashley ; Gill, Jennifer G. ; Martin-Sandoval, Misty ; Yang, Chendong ; Kasitinon, Stacy Y. ; Bezwada, Divya ; Tasdogan, Alpaslan ; Gu, Wen ; Mathews, Thomas P. ; Zhao, Zhiyu ; DeBerardinis, Ralph J. ; Morrison, Sean J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1-11
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Glutaminolysis of CD4+ T Cells: A Potential Therapeutic Target in Viral Diseases
Author / Creator:Xu, Yushan ; Li, Miaomiao ; Lin, Mengjiao ; Cui, Dawei ; Xie, Jue
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Journal of inflammation research, 2024-01, Vol.17, p.603-616
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LRH ‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2 ‐mediated glutaminolysis
Author / Creator:Hu, Jijia ; Zhang, Zongwei ; Hu, Hongtu ; Yang, Keju ; Zhu, Zijing ; Yang, Qian ; Liang, Wei
Publisher:England: John Wiley & Sons, Inc
Journal title:Cell proliferation, 2023-11, Vol.56 (11), p.e13479
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Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
Author / Creator:Peng, Chang ; Jiang, Haowen ; Jing, Liya ; Yang, Wenhua ; Guan, Xiaotong ; Wang, Hanlin ; Yu, Sike ; Cao, Yutang ; Wang, Min ; Ma, Huan ; Lv, Zan ; Gu, Hongyu ; Xia, Chunmei ; Guo, Xiaozhen ; Sun, Bin ; Wang, Aili ; Xie, Cen ; Wu, Wenbiao ; Lu, Luyiyi ; Song, Jiayi ; Lei, Saifei ; Wu, Rui ; Zang, Yi ; Tang, Erjiang ; Li, Jia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1738-20, Article 1738
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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells
Author / Creator:Kono, Michihito ; Yoshida, Nobuya ; Maeda, Kayaho ; Tsokos, George C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (10), p.2478-2483
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Norovirus NS1/2 protein increases glutaminolysis for efficient viral replication
Author / Creator:Hafner, Adam ; Meurs, Noah ; Garner, Ari ; Azar, Elaine ; Kannan, Aditya ; Passalacqua, Karla D. ; Nagrath, Deepak ; Wobus, Christiane E.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-07, Vol.20 (7), p.e1011909
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Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation
Author / Creator:Araujo, Lindsey ; Khim, Phillip ; Mkhikian, Haik ; Mortales, Christie-Lynn ; Demetriou, Michael
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-01, Vol.6
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SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer
Author / Creator:Sniegowski, Tyler ; Korac, Ksenija ; Bhutia, Yangzom D. ; Ganapathy, Vadivel
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-03, Vol.14 (3), p.216
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Myc Regulates a Transcriptional Program That Stimulates Mitochondrial Glutaminolysis and Leads to Glutamine Addiction
Author / Creator:Wise, David R. ; DeBerardinis, Ralph J. ; Mancuso, Anthony ; Sayed, Nabil ; Zhang, Xiao-Yong ; Pfeiffer, Harla K. ; Nissim, Ilana ; Daikhin, Evgueni ; Yudkoff, Marc ; McMahon, Steven B. ; Thompson, Craig B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (48), p.18782-18787
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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis
Author / Creator:Zhang, Xing ; Li, Zheng ; Xuan, Zhe ; Xu, Penghui ; Wang, Weizhi ; Chen, Zheng ; Wang, Sen ; Sun, Guangli ; Xu, Jianghao ; Xu, Zekuan
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2018-12, Vol.37 (1), p.320-22
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Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts
Author / Creator:Bai, Le ; Bernard, Karen ; Tang, Xuebo ; Hu, Min ; Horowitz, Jeffrey C. ; Thannickal, Victor J. ; Sanders, Yan Y.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2019-01, Vol.60 (1), p.49-57
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Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma
Author / Creator:Okazaki, Shogo ; Umene, Kiyoko ; Yamasaki, Juntaro ; Suina, Kentaro ; Otsuki, Yuji ; Yoshikawa, Momoko ; Minami, Yushi ; Masuko, Takashi ; Kawaguchi, Sho ; Nakayama, Hideki ; Banno, Kouji ; Aoki, Daisuke ; Saya, Hideyuki ; Nagano, Osamu
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-11, Vol.110 (11), p.3453-3463
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Showing 1 to 20 of 929 results

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Glutaminolysis as a target for cancer therapy

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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

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Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate–mediated mTOR Activation and Proline Hydroxylation

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GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis

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Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

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Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner

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Targeting ATF4-dependent pro-survival autophagy to synergize glutaminolysis inhibition

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fMiRNA-192 and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma

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Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells

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Glutaminolysis of CD4+ T Cells: A Potential Therapeutic Target in Viral Diseases

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LRH ‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2 ‐mediated glutaminolysis

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Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK

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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells

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Norovirus NS1/2 protein increases glutaminolysis for efficient viral replication

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Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

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SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer

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Myc Regulates a Transcriptional Program That Stimulates Mitochondrial Glutaminolysis and Leads to Glutamine Addiction

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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

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Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts

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Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma

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