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ArticlesPeer ReviewedFull Text
HP1 reshapes nucleosome core to promote phase separation of heterochromatin
Author / Creator:Sanulli, S. ; Trnka, M. J. ; Dharmarajan, V. ; Tibble, R. W. ; Pascal, B. D. ; Burlingame, A. L. ; Griffin, P. R. ; Gross, J. D. ; Narlikar, G. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-11, Vol.575 (7782), p.390-394
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ArticlesPeer ReviewedFull Text
Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
Author / Creator:Larson, Adam G. ; Elnatan, Daniel ; Keenen, Madeline M. ; Trnka, Michael J. ; Johnston, Jonathan B. ; Burlingame, Alma L. ; Agard, David A. ; Redding, Sy ; Narlikar, Geeta J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-07, Vol.547 (7662), p.236-240
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ArticlesPeer ReviewedFull Text
The HP1α-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin
Author / Creator:Loyola, Alejandra ; Tagami, Hideaki ; Bonaldi, Tiziana ; Roche, Danièle ; Quivy, Jean Pierre ; Imhof, Axel ; Nakatani, Yoshihiro ; Dent, Sharon Y R ; Almouzni, Geneviève
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:EMBO reports, 2009-07, Vol.10 (7), p.769-775
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ArticlesPeer ReviewedFull Text
JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin
Author / Creator:Dawson, Mark A. ; Bannister, Andrew J. ; Göttgens, Berthold ; Foster, Samuel D. ; Bartke, Till ; Green, Anthony R. ; Kouzarides, Tony
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7265), p.819-822
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Reference EntriesFull Text
HP1
Publisher:Oxford University Press
Journal title:A Dictionary of Biomedicine, 2019
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ArticlesPeer ReviewedFull Text
Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
Author / Creator:Kilic, Sinan ; Felekyan, Suren ; Doroshenko, Olga ; Boichenko, Iuliia ; Dimura, Mykola ; Vardanyan, Hayk ; Bryan, Louise C. ; Arya, Gaurav ; Seidel, Claus A. M. ; Fierz, Beat
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.235-14, Article 235
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ArticlesPeer ReviewedFull Text
KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA–DNA triplexes and HP1 binding
Author / Creator:Zhang, Xiaoli ; Jiang, Quanlong ; Li, Jiyang ; Zhang, Shiqiang ; Cao, Yaqiang ; Xia, Xian ; Cai, Donghong ; Tan, Jiaqi ; Chen, Jiekai ; Han, Jing-Dong J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2022-11, Vol.24 (11), p.1617-1629
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ArticlesPeer ReviewedFull Text
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Author / Creator:Strom, Amy R ; Biggs, Ronald J ; Banigan, Edward J ; Wang, Xiaotao ; Chiu, Katherine ; Herman, Cameron ; Collado, Jimena ; Yue, Feng ; Ritland Politz, Joan C ; Tait, Leah J ; Scalzo, David ; Telling, Agnes ; Groudine, Mark ; Brangwynne, Clifford P ; Marko, John F ; Stephens, Andrew D
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2021-06, Vol.10
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ArticlesPeer ReviewedFull Text
The HP1 box of KAP1 organizes HP1α for silencing of endogenous retroviral elements in embryonic stem cells
Author / Creator:Gaurav, Nitika ; O’Hara, Ryan ; Hyder, Usman ; Qin, Weihua ; Her, Cheenou ; Romero, Hector ; Kumar, Amarjeet ; Marcaida, Maria J. ; Singh, Rohit K. ; Hovius, Ruud ; Selvam, Karthik ; Liu, Jiuyang ; Martire, Sara ; Yao, Yuhang ; Challa, Ashwini ; Dal Peraro, Matteo ; Fierz, Beat ; Kono, Hidetoshi ; Cardoso, M. Cristina ; Debelouchina, Galia T. ; Leonhardt, Heinrich ; D’Orso, Iván ; Banaszynski, Laura A. ; Kutateladze, Tatiana G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.5066-17
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ArticlesPeer ReviewedFull Text
HP1 locked up: Chromatin
Author / Creator:Du Toit, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2015-03, Vol.16 (3), p.126-126
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ArticlesPeer ReviewedFull Text
HP1 shapes embryonic genome architecture
Author / Creator:Sparmann, Anke
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-05, Vol.28 (5), p.412-412
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ArticlesPeer ReviewedFull Text
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α
Author / Creator:Arnoult, Nausica ; Van Beneden, Amandine ; Decottignies, Anabelle
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2012-09, Vol.19 (9), p.948-956
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ArticlesPeer ReviewedFull Text
HP1 drives de novo 3D genome reorganization in early Drosophila embryos
Author / Creator:Zenk, Fides ; Zhan, Yinxiu ; Kos, Pavel ; Löser, Eva ; Atinbayeva, Nazerke ; Schächtle, Melanie ; Tiana, Guido ; Giorgetti, Luca ; Iovino, Nicola
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-05, Vol.593 (7858), p.289-293
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ArticlesPeer ReviewedFull Text
Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes
Author / Creator:Ostapcuk, Veronika ; Mohn, Fabio ; Carl, Sarah H. ; Basters, Anja ; Hess, Daniel ; Iesmantavicius, Vytautas ; Lampersberger, Lisa ; Flemr, Matyas ; Pandey, Aparna ; Thomä, Nicolas H. ; Betschinger, Joerg ; Bühler, Marc
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-05, Vol.557 (7707), p.739-743
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ArticlesPeer ReviewedFull Text
HP1 locked up
Author / Creator:Du Toit, Andrea
Publisher:London: Nature Publishing Group
Journal title:Nature reviews. Molecular cell biology, 2015-03, Vol.16 (3), p.126-126
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ArticlesPeer ReviewedFull Text
HP1 proteins compact DNA into mechanically and positionally stable phase separated domains
Author / Creator:Keenen, Madeline M ; Brown, David ; Brennan, Lucy D ; Renger, Roman ; Khoo, Harrison ; Carlson, Christopher R ; Huang, Bo ; Grill, Stephan W ; Narlikar, Geeta J ; Redding, Sy
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-03, Vol.10
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ArticlesPeer ReviewedFull Text
Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
Author / Creator:Xiong, Fei ; Wang, Da ; Xiong, Wei ; Wang, Xin ; Huang, Wen-hua ; Wu, Guan-hua ; Liu, Wen-zheng ; Wang, Qi ; Chen, Jun-sheng ; Kuai, Yi-yang ; Wang, Bing ; Chen, Yong-jun
Publisher:England: BioMed Central
Journal title:Journal of experimental & clinical cancer research, 2024-05, Vol.43 (1), p.152-21, Article 152
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ArticlesPeer ReviewedFull Text
Specific Loss of Histone H3 Lysine 9 Trimethylation and HP1γ/Cohesin Binding at D4Z4 Repeats Is Associated with Facioscapulohumeral Dystrophy (FSHD)
Author / Creator:Zeng, Weihua ; de Greef, Jessica C. ; Chen, Yen-Yun ; Chien, Richard ; Kong, Xiangduo ; Gregson, Heather C. ; Winokur, Sara T. ; Pyle, April ; Robertson, Keith D. ; Schmiesing, John A. ; Kimonis, Virginia E. ; Balog, Judit ; Frants, Rune R. ; Ball, Alexander R. ; Lock, Leslie F. ; Donovan, Peter J. ; van der Maarel, Silvère M. ; Yokomori, Kyoko
Publisher:San Francisco, USA: Public Library of Science
Journal title:PLoS genetics, 2009-07, Vol.5 (7), p.e1000559
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ArticlesPeer ReviewedFull Text
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons
Author / Creator:Saint-André, Violaine ; Batsché, Eric ; Rachez, Christophe ; Muchardt, Christian
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2011-03, Vol.18 (3), p.337-344
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ArticlesPeer ReviewedFull Text
HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53
Author / Creator:Yi, Sang Ah ; Lee, Dong Hoon ; Kim, Go Woon ; Ryu, Hyun-Wook ; Park, Jong Woo ; Lee, Jaecheol ; Han, Jihoon ; Park, Jee Hun ; Oh, Hwamok ; Lee, Jieun ; Choi, Junjeong ; Kim, Hyun-Soo ; Kang, Hyeok Gu ; Kim, Da-Hyun ; Chun, Kyung-Hee ; You, Jueng Soo ; Han, Jeung-Whan ; Kwon, So Hee
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2020-09, Vol.27 (9), p.2537-2551
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HP1 reshapes nucleosome core to promote phase separation of heterochromatin

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Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

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The HP1α-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

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JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

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HP1

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Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

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KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA–DNA triplexes and HP1 binding

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HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

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The HP1 box of KAP1 organizes HP1α for silencing of endogenous retroviral elements in embryonic stem cells

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HP1 locked up: Chromatin

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HP1 shapes embryonic genome architecture

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Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α

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HP1 drives de novo 3D genome reorganization in early Drosophila embryos

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Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes

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HP1 locked up

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HP1 proteins compact DNA into mechanically and positionally stable phase separated domains

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Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma

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Specific Loss of Histone H3 Lysine 9 Trimethylation and HP1γ/Cohesin Binding at D4Z4 Repeats Is Associated with Facioscapulohumeral Dystrophy (FSHD)

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Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons

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HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53

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