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Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity
Author / Creator:Fowler, Benjamin J. ; Gelfand, Bradley D. ; Kim, Younghee ; Kerur, Nagaraj ; Tarallo, Valeria ; Hirano, Yoshio ; Amarnath, Shoba ; Fowler, Daniel H. ; Radwan, Marta ; Young, Mark T. ; Pittman, Keir ; Kubes, Paul ; Agarwal, Hitesh K. ; Parang, Keykavous ; Hinton, David R. ; Bastos-Carvalho, Ana ; Li, Shengjian ; Yasuma, Tetsuhiro ; Mizutani, Takeshi ; Yasuma, Reo ; Wright, Charles ; Ambati, Jayakrishna
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6212), p.1000-1003
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Non‐nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability
Author / Creator:Usach, Iris ; Melis, Virginia ; Peris, José‐Esteban
Publisher:Switzerland: International AIDS Society
Journal title:Journal of the International AIDS Society, 2013-01, Vol.16 (1), p.1-n/a
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Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in t...
Author / Creator:Bourgi, Kassem ; Jenkins, Cathy A ; Rebeiro, Peter F ; Palella, Frank ; Moore, Richard D ; Altoff, Keri N ; Gill, John ; Rabkin, Charles S ; Gange, Stephen J ; Horberg, Michael A ; Margolick, Joseph ; Li, Jun ; Wong, Cherise ; Willig, Amanda ; Lima, Viviane D ; Crane, Heidi ; Thorne, Jennifer ; Silverberg, Michael ; Kirk, Gregory ; Mathews, William C ; Sterling, Timothy R ; Lake, Jordan ; Koethe, John R
Publisher:Switzerland: John Wiley & Sons, Inc
Journal title:Journal of the International AIDS Society, 2020-04, Vol.23 (4), p.e25484-n/a
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Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration
Author / Creator:Sabin, Caroline A ; Worm, Signe W ; Weber, Rainer ; Reiss, Peter ; El-Sadr, Wafaa ; Dabis, Francois ; De Wit, Stephane ; Law, Matthew ; D'Arminio Monforte, Antonella ; Friis-Møller, Nina ; Kirk, Ole ; Pradier, Christian ; Weller, Ian ; Phillips, Andrew N ; Lundgren, Jens D
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2008-04, Vol.371 (9622), p.1417-1426
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Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Author / Creator:Vanangamudi, Murugesan ; Palaniappan, Senthilkumar ; Kathiravan, Muthu Kumaradoss ; Namasivayam, Vigneshwaran
Publisher:Basel: MDPI AG
Journal title:Viruses, 2023-09, Vol.15 (10), p.1992
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Dolutegravir Plus Two Nucleoside Reverse Transcriptase Inhibitors versus Efavirenz Plus Two Nucleoside Reverse Transcriptase Inhibitors As Initial Antiretroviral Therapy for People with HIV: A Systema...
Author / Creator:Rutherford, George W. ; Horvath, Hacsi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-10, Vol.11 (10), p.e0162775-e0162775
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Correction to: Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study
Author / Creator:Riou, Julien ; Dupont, Carole ; Bertagnolio, Silvia ; Gupta, Ravindra K. ; Kouyos, Roger D. ; Egger, Matthias ; Althaus, Christian L.
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2021-10, Vol.21 (1), p.1098-1098, Article 1098
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Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study
Author / Creator:Riou, Julien ; Dupont, Carole ; Bertagnolio, Silvia ; Gupta, Ravindra K. ; Kouyos, Roger D. ; Egger, Matthias ; L. Althaus, Christian
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2021-10, Vol.21 (1), p.1042-1042, Article 1042
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Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomise...
Author / Creator:Thompson, Jennifer ; Kityo, Cissy ; Kambugu, Andrew ; Lugemwa, Abbas ; Mwebaze, Raymond ; Thomason, Margaret J ; Mugyenyi, Peter ; Walker, A Sarah ; Bakeinyaga, G ; Kasuswa, S ; Mulima, D ; Musana, H ; Namata, H ; Nkalubo, J ; Okello, P ; Pimundu, G ; Segonga, P ; Ssali, F ; Kayiwa, J ; Tukamushaba, J ; Abunyang, S ; Lwalanda, R ; Namusanje, J ; Katwere, M ; Komujuni, C ; Matovu, J ; Nakajubi, A ; Nalumenya, R ; Semitala, F ; Ssenkindu, T ; Acaku, M ; Ssebutinde, P ; Kukundakwe, J ; Naluguza, M ; Nsibuka, F ; Fortunate, M ; Acen, J ; Achidri, J ; Chamai, M ; Kiconco, M ; Matama, C ; Nambaziira, F ; Rweyora, A ; Tumwebaze, G ; Kiyingi, A ; Senoga, I ; Abwola, M ; Mudoola, M ; Ssennono, F ; Amone, G ; Arach, B ; Bekusike, G ; Bulegyeya, A ; Nassali, A ; Ndukukire ; Ntawiha, H ; Rogers, A ; Kiirya, S ; Balmoi, F ; Kafuma, S ; Phiri, M ; Mudzingwa, S ; Bafana, T ; Chitongo, S ; Lifa, Linly ; Musowa, George ; Mwimaniwa, Grace ; Sikwese, Rosemary ; Ziwoya, Milton ; Kamanga, S ; Makwakwa, T Kayinga E ; Mlenga, M ; Mphande, T ; Mtika, C ; Nyirenda, R ; Mudogo, A ; Wools-Kaloustian, K ; Kunda, I ; Mufwambi, W ; Mulenga, L ; Namfukwe, M ; Kerukadho, E ; Ngwatu, B ; Tebbs, S ; Whittle, J ; Wilkes, H ; Kyomuhendo, F ; Mkandawire, N ; Senyonjo, S ; Angus, B ; Palfreeman, A ; Arribas, J ; Floridia, M ; Walsh, P ; De Rosa, M ; Gilks, C ; Kangewende, A ; van Wyk, J ; Lehrman, S ; Rooney, J
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2018-01, Vol.18 (1), p.47-57
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ArticlesPeer ReviewedFull Text
Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluat...
Author / Creator:Zhuo, Zongji ; Wang, Zhao ; Jing, Lanlan ; Zhang, Tao ; Ge, Anchao ; Zhou, Zhenzhen ; Liu, Ying ; Li, Xin ; De Clercq, Erik ; Pannecouque, Christophe ; Zhan, Peng ; Liu, Xinyong ; Kang, Dongwei
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.9028
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Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised,...
Author / Creator:Margolis, David A, Dr ; Brinson, Cynthia C, MD ; Smith, Graham H R, MD ; de Vente, Jerome, MD ; Hagins, Debbie P, MD ; Eron, Joseph J, Prof ; Griffith, Sandy K, PharmD ; Clair, Marty H St, BS ; Stevens, Marita C, MD ; Williams, Peter E, PhD ; Ford, Susan L, PharmD ; Stancil, Britt S, BS ; Bomar, Melinda M, BS ; Hudson, Krischan J, PhD ; Smith, Kimberly Y, MD ; Spreen, William R, PharmD
Publisher:United States: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2015-10, Vol.15 (10), p.1145-1155
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Nucleoside Reverse Transcriptase Inhibitors Are the Major Class of HIV Antiretroviral Therapeutics That Induce Neuropathic Pain in Mice
Author / Creator:Bush, Keegan ; Wairkar, Yogesh ; Tang, Shao-Jun
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.9059
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The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors
Author / Creator:Fernandes, Lívia da Rocha ; Lopes, Juliana Romano ; Bonjorno, Andressa Francielli ; Prates, João Lucas Bruno ; Scarim, Cauê Benito ; Dos Santos, Jean Leandro
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-11, Vol.15 (11), p.2234
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Clinical benefits of novel non‐nucleoside reverse transcriptase inhibitors: A prospective cohort study
Author / Creator:Ma, Shujing ; Xie, Xiaoxin ; Fu, Yanhua ; Gan, Lin ; Yang, Xiaoyan ; Kong, Linghong ; Li, Jun ; Long, Hai
Publisher:England: John Wiley & Sons, Inc
Journal title:Immunity, Inflammation and Disease, 2024-04, Vol.12 (4), p.e1217-n/a
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Associations between plasma nucleoside reverse transcriptase inhibitors concentrations and cognitive function in people with HIV
Author / Creator:De Francesco, Davide ; Wang, Xinzhu ; Dickinson, Laura ; Underwood, Jonathan ; Bagkeris, Emmanouil ; Babalis, Daphne S. ; Mallon, Patrick W. G. ; Post, Frank A. ; Vera, Jaime H. ; Sachikonye, Memory ; Williams, Ian ; Khoo, Saye ; Sabin, Caroline A. ; Winston, Alan ; Boffito, Marta
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-07, Vol.16 (7), p.e0253861
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Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
Author / Creator:Makarasen, Arthit ; Patnin, Suwicha ; Vijitphan, Pongsit ; Reukngam, Nanthawan ; Khlaychan, Panita ; Kuno, Mayuso ; Intachote, Pakamas ; Saimanee, Busakorn ; Sengsai, Suchada ; Techasakul, Supanna
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-01, Vol.27 (2), p.461
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In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors (NRTIs) but Not by Non-NRTIs
Author / Creator:Hukezalie, Kyle R. ; Thumati, Naresh R. ; Côté, Hélène C. F. ; Wong, Judy M. Y.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e47505
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Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
Author / Creator:Feng, Da ; Lin, Hao ; Jiang, Liyang ; Wang, Zhao ; Sun, Yanying ; Zhou, Zhongxia ; Clercq, Erik De ; Pannecouque, Christophe ; Kang, Dongwei ; Zhan, Peng ; Liu, Xinyong
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7538
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Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration
Author / Creator:Narendran, Siddharth ; Pereira, Felipe ; Yerramothu, Praveen ; Apicella, Ivana ; Wang, Shao-bin ; Ambati, Kameshwari ; Hirahara, Shuichiro ; Kim, Younghee ; Ambati, Meenakshi ; Ambati, Vidya L. ; Huang, Peirong ; Varshney, Akhil ; Nagasaka, Yosuke ; Fukuda, Shinichi ; Baker, Kirstie L. ; Marion, Kenneth M. ; Deussing, Jan M. ; Sadda, Srinivas R. ; Gelfand, Bradley D. ; Ambati, Jayakrishna
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2021-04, Vol.6 (1), p.149-149, Article 149
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Dual therapy with lopinavir and ritonavir plus lamivudine versus triple therapy with lopinavir and ritonavir plus two nucleoside reverse transcriptase inhibitors in antiretroviral-therapy-naive adults...
Author / Creator:Cahn, Pedro, Dr ; Andrade-Villanueva, Jaime, MD ; Arribas, José R, MD ; Gatell, José M, MD ; Lama, Javier R, MD ; Norton, Michael, MD ; Patterson, Patricia, MD ; Madero, Juan Sierra, MD ; Sued, Omar, MD ; Figueroa, Maria Inés, MD ; Rolon, Maria José, MD
Publisher:London: Elsevier Ltd
Journal title:The Lancet infectious diseases, 2014-07, Vol.14 (7), p.572-580
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Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

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Non‐nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability

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Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in t...

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Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration

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Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

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Dolutegravir Plus Two Nucleoside Reverse Transcriptase Inhibitors versus Efavirenz Plus Two Nucleoside Reverse Transcriptase Inhibitors As Initial Antiretroviral Therapy for People with HIV: A Systema...

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Correction to: Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study

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Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study

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Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomise...

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Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluat...

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Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised,...

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Nucleoside Reverse Transcriptase Inhibitors Are the Major Class of HIV Antiretroviral Therapeutics That Induce Neuropathic Pain in Mice

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The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors

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Clinical benefits of novel non‐nucleoside reverse transcriptase inhibitors: A prospective cohort study

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Associations between plasma nucleoside reverse transcriptase inhibitors concentrations and cognitive function in people with HIV

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Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

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In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors (NRTIs) but Not by Non-NRTIs

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Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

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Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration

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Dual therapy with lopinavir and ritonavir plus lamivudine versus triple therapy with lopinavir and ritonavir plus two nucleoside reverse transcriptase inhibitors in antiretroviral-therapy-naive adults...

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