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The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 −) advanced/metastatic breast cancer
Author / Creator:Bardia, Aditya ; Mayer, Ingrid ; Winer, Eric ; Linden, Hannah M. ; Ma, Cynthia X. ; Parker, Barbara A. ; Bellet, Meritxell ; Arteaga, Carlos L. ; Cheeti, Sravanthi ; Gates, Mary ; Chang, Ching-Wei ; Fredrickson, Jill ; Spoerke, Jill M. ; Moore, Heather M. ; Giltnane, Jennifer ; Friedman, Lori S. ; Chow Maneval, Edna ; Chan, Iris ; Jhaveri, Komal
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2023-01, Vol.197 (2), p.319-331
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The oral selective estrogen receptor degrader GDC-0810
Author / Creator:Linden, Hannah M ; Bardia, Aditya ; Ma, Cynthia X ; Parker, Barbara A ; Bellet, Meritxell ; Mayer, Ingrid ; Winer, Eric
Publisher:Springer
Journal title:Breast cancer research and treatment, 2023-01, Vol.197 (2), p.319
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GLL398, an oral selective estrogen receptor degrader
Author / Creator:Wang, Guangdi ; Guo, Shanchun ; Zhang, Changde ; Hossain, Ahamed ; Mottamal, Madhusoodanan ; Liu, Jiawang
Publisher:Springer
Journal title:Breast cancer research and treatment, 2020-04, Vol.180 (2), p.359
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GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models
Author / Creator:Guo, Shanchun ; Zhang, Changde ; Mottamal, Madhusoodanan ; Hossain, Ahamed ; Liu, Jiawang ; Wang, Guangdi
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2020-04, Vol.180 (2), p.359-368
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Phase 1 study of oral selective estrogen receptor degrader
Author / Creator:Tamura, Kenji ; Mukohara, Toru ; Yonemori, Kan ; Kawabata, Yumiko ; Nicolas, Xavier ; Tanaka, Tomoyuki ; Iwata, Hiroji
Publisher:Springer
Journal title:Breast cancer (Tokyo, Japan), 2023-05, Vol.30 (3), p.506
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The oral selective estrogen receptor degrader GDC-0810 advanced/metastatic breast cancer
Author / Creator:Bardia, Aditya ; Mayer, Ingrid ; Winer, Eric ; Linden, Hannah M ; Ma, Cynthia X ; Parker, Barbara A ; Bellet, Meritxell
Publisher:Springer
Journal title:Breast cancer research and treatment, 2023-01, Vol.197 (2), p.319
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G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer
Author / Creator:Andreano, Kaitlyn J. ; Wardell, Suzanne E. ; Baker, Jennifer G. ; Desautels, Taylor K. ; Baldi, Robert ; Chao, Christina A. ; Heetderks, Kendall A. ; Bae, Yeeun ; Xiong, Rui ; Tonetti, Debra A. ; Gutgesell, Lauren M. ; Zhao, Jiong ; Sorrentino, Jessica A. ; Thompson, Delita A. ; Bisi, John E. ; Strum, Jay C. ; Thatcher, Gregory R. J. ; Norris, John D.
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2020-04, Vol.180 (3), p.635-646
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Phase 1 study of oral selective estrogen receptor degrader (SERD) amcenestrant (SAR439859), in Japanese women with ER-positive and HER2-negative advanced breast cancer (AMEERA-2)
Author / Creator:Tamura, Kenji ; Mukohara, Toru ; Yonemori, Kan ; Kawabata, Yumiko ; Nicolas, Xavier ; Tanaka, Tomoyuki ; Iwata, Hiroji
Publisher:Singapore: Springer Nature Singapore
Journal title:Breast cancer (Tokyo, Japan), 2023-05, Vol.30 (3), p.506-517
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Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degrader
Author / Creator:Besret, Laurent ; d’Heilly, Sébastien ; Aubert, Cathy ; Bluet, Guillaume ; Gruss-Leleu, Florence ; Le-Gall, Françoise ; Caron, Anne ; Andrieu, Laurent ; Vincent, Sylvie ; Shomali, Maysoun ; Bouaboula, Monsif ; Voland, Carole ; Ming, Jeffrey ; Roy, Sébastien ; Rao, Srinivas ; Carrez, Chantal ; Jouannot, Erwan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:EJNMMI research, 2020-06, Vol.10 (1), p.70-70, Article 70
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SAT-341 Pharmacology and Metabolism of GLL398 an Oral Selective Estrogen Receptor Degrader for Endocrine Therapy of Breast Cancer
Author / Creator:Guo, Shanchun ; Hossain, Ahamed ; Zhang, Changde ; Mottamal, Madhu ; Liu, Jiawang ; Wiese, Thomas ; Wang, Guangdi
Publisher:Washington, DC: Endocrine Society
Journal title:Journal of the Endocrine Society, 2019-04, Vol.3 (Supplement_1)
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ArticlesPeer ReviewedFull Text
Estrogen Receptor Signaling in the Immune System
Author / Creator:Chakraborty, Binita ; Byemerwa, Jovita ; Krebs, Taylor ; Lim, Felicia ; Chang, Ching-Yi ; McDonnell, Donald P
Publisher:US: Oxford University Press
Journal title:Endocrine reviews, 2023-02, Vol.44 (1), p.117-141
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ArticlesPeer ReviewedFull Text
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells
Author / Creator:Fanning, Sean W ; Jeselsohn, Rinath ; Dharmarajan, Venkatasubramanian ; Mayne, Christopher G ; Karimi, Mostafa ; Buchwalter, Gilles ; Houtman, René ; Toy, Weiyi ; Fowler, Colin E ; Han, Ross ; Lainé, Muriel ; Carlson, Kathryn E ; Martin, Teresa A ; Nowak, Jason ; Nwachukwu, Jerome C ; Hosfield, David J ; Chandarlapaty, Sarat ; Tajkhorshid, Emad ; Nettles, Kendall W ; Griffin, Patrick R ; Shen, Yang ; Katzenellenbogen, John A ; Brown, Myles ; Greene, Geoffrey L
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2018-11, Vol.7
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Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells
Author / Creator:Dubash, Taronish D. ; Bardia, Aditya ; Chirn, Brian ; Reeves, Brittany A. ; LiCausi, Joseph A. ; Burr, Risa ; Wittner, Ben S. ; Rai, Sumit ; Patel, Hitisha ; Bihani, Teeru ; Arlt, Heike ; Bidard, Francois-Clement ; Kaklamani, Virginia G. ; Aftimos, Philippe ; Cortés, Javier ; Scartoni, Simona ; Fiascarelli, Alessio ; Binaschi, Monica ; Habboubi, Nassir ; Iafrate, A. John ; Toner, Mehmet ; Haber, Daniel A. ; Maheswaran, Shyamala
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2023-08, Vol.201 (1), p.43-56
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EMERALD: Phase III trial of elacestrant (RAD1901) vs endocrine therapy for previously treated ER+ advanced breast cancer
Author / Creator:Bardia, Aditya ; Aftimos, Philippe ; Bihani, Teeru ; Anderson-Villaluz, Alfred T ; Jung, JungAh ; Conlan, Maureen G ; Kaklamani, Virginia G
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2019-10, Vol.15 (28), p.3209-3218
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AMEERA-5: a randomized, double-blind phase 3 study of amcenestrant plus palbociclib versus letrozole plus palbociclib for previously untreated ER+/HER2– advanced breast cancer
Author / Creator:Bardia, Aditya ; Cortes, Javier ; Hurvitz, Sara A. ; Delaloge, Suzette ; Iwata, Hiroji ; Shao, Zhi-Ming ; Kanagavel, Dheepak ; Cohen, Patrick ; Liu, Qianying ; Cartot-Cotton, Sylvaine ; Pelekanou, Vasiliki ; O’Shaughnessy, Joyce
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2022, Vol.14, p.17588359221083956-17588359221083956
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Findings from College of Medicine Yields New Data on Breast Cancer [Imlunestrant Selective Estrogen Receptor Degrader Treatment of Breast Cancer]
Publisher:NewsRX LLC
Journal title:Women's health weekly, 2023-03, p.170
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Fulvestrant-3-Boronic Acid (ZB716) Demonstrates Oral Bioavailability and Favorable Pharmacokinetic Profile in Preclinical ADME Studies
Author / Creator:Liu, Jiawang ; Rajasekaran, Nirmal ; Hossain, Ahamed ; Zhang, Changde ; Guo, Shanchun ; Kang, Borui ; Jung, Hunsoon ; Kim, Hongjoong ; Wang, Guangdi
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-07, Vol.14 (8), p.719
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"Selective Estrogen Receptor Degrader" in Patent Application Approval Process
Publisher:NewsRX LLC
Journal title:Women's health weekly, 2021-02, p.52
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Elacestrant plus alpelisib in an ESR1 and PIK3CA co-mutated and heavily pretreated metastatic breast cancer: the first case report for combination efficacy and safety
Author / Creator:Tokat, Ünal Metin ; Bilgiç, Şevval Nur ; Aydın, Esranur ; Adibi, Ashkan ; Özgü, Eylül ; Tutar, Onur ; Demiray, Mutlu
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2024-01, Vol.16, p.17588359241297101
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New Findings from Massachusetts General Hospital in Breast Cancer Provides New Insights [The Oral Selective Estrogen Receptor Degrader Gdc-0810 ...]
Publisher:NewsRX LLC
Journal title:Women's health weekly, 2022-12, p.2910
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Showing 1 to 20 of 296 results

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The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 −) advanced/metastatic breast cancer

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The oral selective estrogen receptor degrader GDC-0810

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GLL398, an oral selective estrogen receptor degrader

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GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models

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Phase 1 study of oral selective estrogen receptor degrader

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The oral selective estrogen receptor degrader GDC-0810 advanced/metastatic breast cancer

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G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

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Phase 1 study of oral selective estrogen receptor degrader (SERD) amcenestrant (SAR439859), in Japanese women with ER-positive and HER2-negative advanced breast cancer (AMEERA-2)

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Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degrader

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SAT-341 Pharmacology and Metabolism of GLL398 an Oral Selective Estrogen Receptor Degrader for Endocrine Therapy of Breast Cancer

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Estrogen Receptor Signaling in the Immune System

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The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

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Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells

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EMERALD: Phase III trial of elacestrant (RAD1901) vs endocrine therapy for previously treated ER+ advanced breast cancer

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AMEERA-5: a randomized, double-blind phase 3 study of amcenestrant plus palbociclib versus letrozole plus palbociclib for previously untreated ER+/HER2– advanced breast cancer

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Findings from College of Medicine Yields New Data on Breast Cancer [Imlunestrant Selective Estrogen Receptor Degrader Treatment of Breast Cancer]

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Fulvestrant-3-Boronic Acid (ZB716) Demonstrates Oral Bioavailability and Favorable Pharmacokinetic Profile in Preclinical ADME Studies

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"Selective Estrogen Receptor Degrader" in Patent Application Approval Process

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Elacestrant plus alpelisib in an ESR1 and PIK3CA co-mutated and heavily pretreated metastatic breast cancer: the first case report for combination efficacy and safety

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New Findings from Massachusetts General Hospital in Breast Cancer Provides New Insights [The Oral Selective Estrogen Receptor Degrader Gdc-0810 ...]

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