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1,584 results for src-Family+Kinases+-+metabolism

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ArticlesPeer ReviewedFull Text
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
Author / Creator:Yoshida, Soichiro ; Tsutsumi, Shinji ; Muhlebach, Guillaume ; Sourbier, Carole ; Lee, Min-Jung ; Lee, Sunmin ; Vartholomaiou, Evangelia ; Tatokoro, Manabu ; Beebe, Kristin ; Miyajima, Naoto ; Mohney, Robert P. ; Chen, Yang ; Hasumi, Hisashi ; Xu, Wanping ; Fukushima, Hiroshi ; Nakamura, Ken ; Koga, Fumitaka ; Kihara, Kazunori ; Trepel, Jane ; Picard, Didier ; Neckers, Leonard
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.E1604-E1612
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Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
Author / Creator:Pastushenko, Ievgenia ; Mauri, Federico ; Song, Yura ; de Cock, Florian ; Meeusen, Bob ; Swedlund, Benjamin ; Impens, Francis ; Van Haver, Delphi ; Opitz, Matthieu ; Thery, Manuel ; Bareche, Yacine ; Lapouge, Gaelle ; Vermeersch, Marjorie ; Van Eycke, Yves-Rémi ; Balsat, Cédric ; Decaestecker, Christine ; Sokolow, Youri ; Hassid, Sergio ; Perez-Bustillo, Alicia ; Agreda-Moreno, Beatriz ; Rios-Buceta, Luis ; Jaen, Pedro ; Redondo, Pedro ; Sieira-Gil, Ramon ; Millan-Cayetano, Jose F. ; Sanmatrtin, Onofre ; D’Haene, Nicky ; Moers, Virginie ; Rozzi, Milena ; Blondeau, Jeremy ; Lemaire, Sophie ; Scozzaro, Samuel ; Janssens, Veerle ; De Troya, Magdalena ; Dubois, Christine ; Pérez-Morga, David ; Salmon, Isabelle ; Sotiriou, Christos ; Helmbacher, Francoise ; Blanpain, Cédric
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-01, Vol.589 (7842), p.448-455
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Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Author / Creator:Liu, Haipeng ; Zhang, Haiping ; Wu, Xiangyang ; Ma, Dapeng ; Wu, Juehui ; Wang, Lin ; Jiang, Yan ; Fei, Yiyan ; Zhu, Chenggang ; Tan, Rong ; Jungblut, Peter ; Pei, Gang ; Dorhoi, Anca ; Yan, Qiaoling ; Zhang, Fan ; Zheng, Ruijuan ; Liu, Siyu ; Liang, Haijiao ; Liu, Zhonghua ; Yang, Hua ; Chen, Jianxia ; Wang, Peng ; Tang, Tianqi ; Peng, Wenxia ; Hu, Zhangsen ; Xu, Zhu ; Huang, Xiaochen ; Wang, Jie ; Li, Haohao ; Zhou, Yilong ; Liu, Feng ; Yan, Dapeng ; Kaufmann, Stefan H. E. ; Chen, Chang ; Mao, Zhiyong ; Ge, Baoxue
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-11, Vol.563 (7729), p.131-136
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Mechano-modulatory synthetic niches for liver organoid derivation
Author / Creator:Sorrentino, Giovanni ; Rezakhani, Saba ; Yildiz, Ece ; Nuciforo, Sandro ; Heim, Markus H. ; Lutolf, Matthias P. ; Schoonjans, Kristina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-07, Vol.11 (1), p.3416-3416, Article 3416
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Proteogenomics connects somatic mutations to signalling in breast cancer
Author / Creator:Mertins, Philipp ; Mani, D. R. ; Ruggles, Kelly V. ; Gillette, Michael A. ; Clauser, Karl R. ; Wang, Pei ; Wang, Xianlong ; Qiao, Jana W. ; Cao, Song ; Petralia, Francesca ; Kawaler, Emily ; Mundt, Filip ; Krug, Karsten ; Tu, Zhidong ; Lei, Jonathan T. ; Gatza, Michael L. ; Wilkerson, Matthew ; Perou, Charles M. ; Yellapantula, Venkata ; Huang, Kuan-lin ; Lin, Chenwei ; McLellan, Michael D. ; Yan, Ping ; Davies, Sherri R. ; Townsend, R. Reid ; Skates, Steven J. ; Wang, Jing ; Zhang, Bing ; Kinsinger, Christopher R. ; Mesri, Mehdi ; Rodriguez, Henry ; Ding, Li ; Paulovich, Amanda G. ; Fenyö, David ; Ellis, Matthew J. ; Carr, Steven A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-06, Vol.534 (7605), p.55-62
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Activation pathway of Src kinase reveals intermediate states as targets for drug design
Author / Creator:Shukla, Diwakar ; Meng, Yilin ; Roux, Benoît ; Pande, Vijay S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-03, Vol.5 (1), p.3397-3397, Article 3397
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SRC kinase-mediated signaling pathways and targeted therapies in breast cancer
Author / Creator:Luo, Juan ; Zou, Hailin ; Guo, Yibo ; Tong, Tongyu ; Ye, Liping ; Zhu, Chengming ; Deng, Liang ; Wang, Bo ; Pan, Yihang ; Li, Peng
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2022-12, Vol.24 (1), p.99-99, Article 99
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ArticlesPeer ReviewedFull Text
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Author / Creator:Calvo, Fernando ; Ege, Nil ; Grande-Garcia, Araceli ; Hooper, Steven ; Jenkins, Robert P. ; Chaudhry, Shahid I. ; Harrington, Kevin ; Williamson, Peter ; Moeendarbary, Emad ; Charras, Guillaume ; Sahai, Erik
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-06, Vol.15 (6), p.637-646
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Aryl hydrocarbon receptor control of a disease tolerance defence pathway
Author / Creator:Bessede, Alban ; Gargaro, Marco ; Pallotta, Maria T. ; Matino, Davide ; Servillo, Giuseppe ; Brunacci, Cinzia ; Bicciato, Silvio ; Mazza, Emilia M. C. ; Macchiarulo, Antonio ; Vacca, Carmine ; Iannitti, Rossana ; Tissi, Luciana ; Volpi, Claudia ; Belladonna, Maria L. ; Orabona, Ciriana ; Bianchi, Roberta ; Lanz, Tobias V. ; Platten, Michael ; Della Fazia, Maria A. ; Piobbico, Danilo ; Zelante, Teresa ; Funakoshi, Hiroshi ; Nakamura, Toshikazu ; Gilot, David ; Denison, Michael S. ; Guillemin, Gilles J. ; DuHadaway, James B. ; Prendergast, George C. ; Metz, Richard ; Geffard, Michel ; Boon, Louis ; Pirro, Matteo ; Iorio, Alfonso ; Veyret, Bernard ; Romani, Luigina ; Grohmann, Ursula ; Fallarino, Francesca ; Puccetti, Paolo
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-07, Vol.511 (7508), p.184-190
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Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis
Author / Creator:Jin, L ; Chun, J ; Pan, C ; Alesi, G N ; Li, D ; Magliocca, K R ; Kang, Y ; Chen, Z G ; Shin, D M ; Khuri, F R ; Fan, J ; Kang, S
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-07, Vol.36 (27), p.3797-3806
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Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses
Author / Creator:Wu, Jun ; Li, Gen ; Li, Le ; Li, Dan ; Dong, Zhongjun ; Jiang, Peng
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2021-01, Vol.23 (1), p.75-86
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ArticlesPeer ReviewedFull Text
Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second
Author / Creator:Strohmeyer, Nico ; Bharadwaj, Mitasha ; Costell, Mercedes ; Fässler, Reinhard ; Müller, Daniel J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature materials, 2017-12, Vol.16 (12), p.1262-1270
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ArticlesPeer ReviewedFull Text
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
Author / Creator:Janzer, Andreas ; German, Natalie J. ; Gonzalez-Herrera, Karina N. ; Asara, John M. ; Haigis, Marcia C. ; Struhl, Kevin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10574-10579
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Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis
Author / Creator:Li, Rongkun ; Wang, Yahui ; Zhang, Xiaoxin ; Feng, Mingxuan ; Ma, Jun ; Li, Jun ; Yang, Xiaomei ; Fang, Fang ; Xia, Qiang ; Zhang, Zhigang ; Shang, Mingyi ; Jiang, Shuheng
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2019-01, Vol.18 (1), p.18-18, Article 18
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LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling
Author / Creator:Zhang, Shanyi ; Ma, Hanyu ; Zhang, Daming ; Xie, Shule ; Wang, Weiwei ; Li, Qunxing ; Lin, Zhaoyu ; Wang, Youyuan
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-07, Vol.9 (7), p.742-16, Article 742
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Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation
Author / Creator:Zheng, Jian ; Huang, Xudong ; Tan, Wen ; Yu, Dianke ; Du, Zhongli ; Chang, Jiang ; Wei, Lixuan ; Han, Yaling ; Wang, Chengfeng ; Che, Xu ; Zhou, Yifeng ; Miao, Xiaoping ; Jiang, Guoliang ; Yu, Xianjun ; Yang, Xianghong ; Cao, Guangwen ; Zuo, Chaohui ; Li, Zhaoshen ; Wang, Chunyou ; Cheung, Siu Tim ; Jia, Yongfeng ; Zheng, Xiongwei ; Shen, Hongbing ; Wu, Chen ; Lin, Dongxin
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-07, Vol.48 (7), p.747-757
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Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy
Author / Creator:Zhou, Changqian ; Ma, Kaili ; Gao, Ruize ; Mu, Chenglong ; Chen, Linbo ; Liu, Qiangqiang ; Luo, Qian ; Feng, Du ; Zhu, Yushan ; Chen, Quan
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2017-02, Vol.27 (2), p.184-201
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Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition
Author / Creator:Ortiz, Maria A. ; Mikhailova, Tatiana ; Li, Xiang ; Porter, Baylee A. ; Bah, Alaji ; Kotula, Leszek
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2021-06, Vol.19 (1), p.67-19, Article 67
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Erythropoietin protects the inner blood–retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy
Author / Creator:Xie, Hai ; Zhang, Chaoyang ; Liu, Dandan ; Yang, Qian ; Tang, Lei ; Wang, Tianqin ; Tian, Haibin ; Lu, Lixia ; Xu, Jing-Ying ; Gao, Furong ; Wang, Juan ; Jin, Caixia ; Li, Weiye ; Xu, Guoxu ; Xu, Guo-Tong ; Zhang, Jingfa
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2021-01, Vol.64 (1), p.211-225
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Receptor-mediated mitophagy in yeast and mammalian systems
Author / Creator:Liu, Lei ; Sakakibara, Kaori ; Chen, Quan ; Okamoto, Koji
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2014-07, Vol.24 (7), p.787-795
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Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

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Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

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Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

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Mechano-modulatory synthetic niches for liver organoid derivation

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Proteogenomics connects somatic mutations to signalling in breast cancer

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Activation pathway of Src kinase reveals intermediate states as targets for drug design

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SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

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Aryl hydrocarbon receptor control of a disease tolerance defence pathway

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Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis

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Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses

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Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

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Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

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LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling

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Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

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Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy

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Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition

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Erythropoietin protects the inner blood–retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy

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Receptor-mediated mitophagy in yeast and mammalian systems

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