Osteoblast expression of an engineered G s -coupled receptor dramatically increases bone mass
Osteoblast expression of an engineered G s -coupled receptor dramatically increases bone mass
About this item
Full title
Osteoblast expression of an engineered G s -coupled receptor dramatically increases bone mass
Author / Creator
Journal title
Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (4), p.1209-1214
Language
English
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Scope and Contents
Contents
Osteoblasts are essential for maintaining bone mass, avoiding osteoporosis, and repairing injured bone. Activation of osteoblast G protein-coupled receptors (GPCRs), such as the parathyroid hormone receptor, can increase bone mass; however, the anabolic mechanisms are poorly understood. Here we use “Rs1,” an engineered GPCR with constitutive G
s...
Alternative Titles
Full title
Osteoblast expression of an engineered G s -coupled receptor dramatically increases bone mass
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_0707457105
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_0707457105
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0707457105
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