InsP 7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
InsP 7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
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Publisher
United States
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English
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United States
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Regulation of enzymatic 5' decapping of messenger RNA (mRNA), which normally commits transcripts to their destruction, has the capacity to dynamically reshape the transcriptome. For example, protection from 5' decapping promotes accumulation of mRNAs into processing (P) bodies-membraneless, biomolecular condensates. Such compartmentalization of mRN...
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InsP 7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
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TN_cdi_crossref_primary_10_1073_pnas_1922284117
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1922284117
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1922284117
