A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-...
A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Static
in vitro
cell culture studies cannot capture the dynamic concentration profiles of drugs, nutrients, and other factors that cells experience in physiological systems. This limits the confidence in the translational relevance of
in vitro
experiments and increases the reliance on empirical testing of exposure-response relationships...
Alternative Titles
Full title
A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships
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Record Identifier
TN_cdi_crossref_primary_10_1208_s12248_020_0430_y
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1208_s12248_020_0430_y
Other Identifiers
ISSN
1550-7416
E-ISSN
1550-7416
DOI
10.1208/s12248-020-0430-y