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A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-...

A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1208_s12248_020_0430_y

A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships

About this item

Full title

A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships

Publisher

Cham: Springer International Publishing

Journal title

The AAPS journal, 2020-03, Vol.22 (2), p.53, Article 53

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Static
in vitro
cell culture studies cannot capture the dynamic concentration profiles of drugs, nutrients, and other factors that cells experience in physiological systems. This limits the confidence in the translational relevance of
in vitro
experiments and increases the reliance on empirical testing of exposure-response relationships...

Alternative Titles

Full title

A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1208_s12248_020_0430_y

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1208_s12248_020_0430_y

Other Identifiers

ISSN

1550-7416

E-ISSN

1550-7416

DOI

10.1208/s12248-020-0430-y

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