Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
About this item
Full title
Author / Creator
Loh, Marie , Zhang, Weihua , Ng, Hong Kiat , Schmid, Katharina , Lamri, Amel , Tong, Lin , Ahmad, Meraj , Lee, Jung-Jin , Ng, Maggie C. Y. , Petty, Lauren E. , Spracklen, Cassandra N. , Takeuchi, Fumihiko , Islam, Md. Tariqul , Jasmine, Farzana , Kasturiratne, Anuradhani , Kibriya, Muhammad , Mohlke, Karen L. , Paré, Guillaume , Prasad, Gauri , Shahriar, Mohammad , Chee, Miao Ling , de Silva, H. Janaka , Engert, James C. , Gerstein, Hertzel C. , Mani, K. Radha , Sabanayagam, Charumathi , Vujkovic, Marijana , Wickremasinghe, Ananda R. , Wong, Tien Yin , Yajnik, Chittaranjan S. , Yusuf, Salim , Ahsan, Habibul , Bharadwaj, Dwaipayan , Anand, Sonia S. , Below, Jennifer E. , Boehnke, Michael , Bowden, Donald W. , Chandak, Giriraj R. , Cheng, Ching-Yu , Kato, Norihiro , Mahajan, Anubha , Sim, Xueling , McCarthy, Mark I. , Morris, Andrew P. , Kooner, Jaspal S. , Saleheen, Danish and Chambers, John C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide association meta-analysis with South Asian T2D cases (
n
= 16,677) and controls (
n
= 33,856), followed by combined analyses with Europeans (n
eff
= 231,420). We identify 21 novel genetic loci for significant association with T2D (
Alternative Titles
Full title
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
Authors, Artists and Contributors
Author / Creator
Zhang, Weihua
Ng, Hong Kiat
Schmid, Katharina
Lamri, Amel
Tong, Lin
Ahmad, Meraj
Lee, Jung-Jin
Ng, Maggie C. Y.
Petty, Lauren E.
Spracklen, Cassandra N.
Takeuchi, Fumihiko
Islam, Md. Tariqul
Jasmine, Farzana
Kasturiratne, Anuradhani
Kibriya, Muhammad
Mohlke, Karen L.
Paré, Guillaume
Prasad, Gauri
Shahriar, Mohammad
Chee, Miao Ling
de Silva, H. Janaka
Engert, James C.
Gerstein, Hertzel C.
Mani, K. Radha
Sabanayagam, Charumathi
Vujkovic, Marijana
Wickremasinghe, Ananda R.
Wong, Tien Yin
Yajnik, Chittaranjan S.
Yusuf, Salim
Ahsan, Habibul
Bharadwaj, Dwaipayan
Anand, Sonia S.
Below, Jennifer E.
Boehnke, Michael
Bowden, Donald W.
Chandak, Giriraj R.
Cheng, Ching-Yu
Kato, Norihiro
Mahajan, Anubha
Sim, Xueling
McCarthy, Mark I.
Morris, Andrew P.
Kooner, Jaspal S.
Saleheen, Danish
Chambers, John C.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_07ab4de945a54b4f8a1b8fb3e19f5d29
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07ab4de945a54b4f8a1b8fb3e19f5d29
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03248-5
