Mathematical modelling identifies conditions for maintaining and escaping feedback control in the in...
Mathematical modelling identifies conditions for maintaining and escaping feedback control in the intestinal epithelium
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The intestinal epithelium is one of the fastest renewing tissues in mammals. It shows a hierarchical organisation, where intestinal stem cells at the base of crypts give rise to rapidly dividing transit amplifying cells that in turn renew the pool of short-lived differentiated cells. Upon injury and stem-cell loss, cells can also de-differentiate....
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Full title
Mathematical modelling identifies conditions for maintaining and escaping feedback control in the intestinal epithelium
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TN_cdi_doaj_primary_oai_doaj_org_article_13af6fc323474021ac487c1696cf78dc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13af6fc323474021ac487c1696cf78dc
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-09202-z
