Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T...
Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells
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Author / Creator
Zhang, Yuanyuan , Ge, Tong , Huang, Meijuan , Qin, Yun , Liu, Tianjiao , Mu, Wei , Wang, Gaoxiang , Jiang, Lijun , Li, Tongjuan , Zhao, Lei and Wang, Jue
Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
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Publication information
Publisher
New Zealand: Dove Medical Press Limited
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Scope and Contents
Contents
CAR-T cell therapy is effective in the treatment of certain hematological malignancies, and the expansion and functional persistence of CAR-T cells in vivo are crucial to clinical efficacy. The aim of this study was to investigate the potential of extracellular vesicles (EVs) modified with the CAR antigen to promote the efficacy of CAR-T cells in v...
Alternative Titles
Full title
Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_158d48772d6243218d9af9b112a1a5b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_158d48772d6243218d9af9b112a1a5b9
Other Identifiers
ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S390720