Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year surv...
Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial
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Full title
Author / Creator
Ascierto, Paolo A. , Casula, Milena , Bulgarelli, Jenny , Pisano, Marina , Piccinini, Claudia , Piccin, Luisa , Cossu, Antonio , Mandalà, Mario , Ferrucci, Pier Francesco , Guidoboni, Massimo , Rutkowski, Piotr , Ferraresi, Virginia , Arance, Ana , Guida, Michele , Maiello, Evaristo , Gogas, Helen , Richtig, Erika , Fierro, Maria Teresa , Lebbe, Celeste , Helgadottir, Hildur , Queirolo, Paola , Spagnolo, Francesco , Tucci, Marco , Del Vecchio, Michele , Cao, Maria Gonzales , Minisini, Alessandro Marco , De Placido, Sabino , Sanmamed, Miguel F. , Mallardo, Domenico , Paone, Miriam , Vitale, Maria Grazia , Melero, Ignacio , Grimaldi, Antonio M. , Giannarelli, Diana , Dummer, Reinhard , Sileni, Vanna Chiarion and Palmieri, Giuseppe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
No prospective data were available prior to 2021 to inform selection between combination BRAF and MEK inhibition versus dual blockade of programmed cell death protein-1 (PD-1) and cytotoxic T lymphocyte antigen-4 (CTLA-4) as first-line treatment options for
BRAFV
600-mutant melanoma. SECOMBIT (NCT02631447) was a randomized, three-arm, noncomp...
Alternative Titles
Full title
Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial
Authors, Artists and Contributors
Author / Creator
Casula, Milena
Bulgarelli, Jenny
Pisano, Marina
Piccinini, Claudia
Piccin, Luisa
Cossu, Antonio
Mandalà, Mario
Ferrucci, Pier Francesco
Guidoboni, Massimo
Rutkowski, Piotr
Ferraresi, Virginia
Arance, Ana
Guida, Michele
Maiello, Evaristo
Gogas, Helen
Richtig, Erika
Fierro, Maria Teresa
Lebbe, Celeste
Helgadottir, Hildur
Queirolo, Paola
Spagnolo, Francesco
Tucci, Marco
Del Vecchio, Michele
Cao, Maria Gonzales
Minisini, Alessandro Marco
De Placido, Sabino
Sanmamed, Miguel F.
Mallardo, Domenico
Paone, Miriam
Vitale, Maria Grazia
Melero, Ignacio
Grimaldi, Antonio M.
Giannarelli, Diana
Dummer, Reinhard
Sileni, Vanna Chiarion
Palmieri, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2b98c18ea9d84e45baec87cc1752497f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b98c18ea9d84e45baec87cc1752497f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44475-6
