Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diag...
Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies
About this item
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Author / Creator
Kuilman, Thomas , Schrikkema, Deborah S. , Gadiot, Jules , Gomez-Eerland, Raquel , Bies, Laura , Walker, Julia , Spaapen, Robbert M. , Kok, Hanna , Houg, Demi , Viyacheva, Milena , Claassen, Yvonne B. , Saornil, Manuel , Krijgsman, Oscar , Stringer, Bas , Ding, Huiwen , Geleijnse, Anou , Meinema, Anne C. , Weissbrich, Bianca , Lancee, Melissa , Engele, Carmen G. , Sabatino, Marianna , Chen, Pei-Ling , Tsai, Kenneth Y. , Mulé, James J. , Sondak, Vernon K. , van den Bulk, Jitske , de Miranda, Noel F. , Jedema, Inge , Haanen, John G. , van Heijst, Jeroen W. J. , Schumacher, Ton N. , Linnemann, Carsten and Bendle, Gavin M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) can mediate tumor regression, including complete and durable responses, in a range of solid cancers, most notably in melanoma. However, its wider application and efficacy has been restricted by the limited accessibility, proliferative capacity and effector function of tumor-specific TI...
Alternative Titles
Full title
Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies
Authors, Artists and Contributors
Author / Creator
Schrikkema, Deborah S.
Gadiot, Jules
Gomez-Eerland, Raquel
Bies, Laura
Walker, Julia
Spaapen, Robbert M.
Kok, Hanna
Houg, Demi
Viyacheva, Milena
Claassen, Yvonne B.
Saornil, Manuel
Krijgsman, Oscar
Stringer, Bas
Ding, Huiwen
Geleijnse, Anou
Meinema, Anne C.
Weissbrich, Bianca
Lancee, Melissa
Engele, Carmen G.
Sabatino, Marianna
Chen, Pei-Ling
Tsai, Kenneth Y.
Mulé, James J.
Sondak, Vernon K.
van den Bulk, Jitske
de Miranda, Noel F.
Jedema, Inge
Haanen, John G.
van Heijst, Jeroen W. J.
Schumacher, Ton N.
Linnemann, Carsten
Bendle, Gavin M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2d76c4e060a14eb1ad32c85894d62d96
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2d76c4e060a14eb1ad32c85894d62d96
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55420-6