A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells
A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells
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Author / Creator
Appelberg, Sofia , Ahlén, Gustaf , Yan, Jingyi , Nikouyan, Negin , Weber, Sofie , Larsson, Olivia , Höglund, Urban , Aleman, Soo , Weber, Friedemann , Perlhamre, Emma , Apro, Johanna , Gidlund, Eva‐Karin , Tuvesson, Ola , Salati, Simona , Cadossi, Matteo , Tegel, Hanna , Hober, Sophia , Frelin, Lars , Mirazimi, Ali and Sällberg, Matti
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO. We designed a more universal SARS‐CoV‐2 DNA vaccine containing receptor‐binding domain loops from the huCoV‐19/WH01, the Alpha, and the Beta variants, com...
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Full title
A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_35ec9af66e3647f5894151746b9c3202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35ec9af66e3647f5894151746b9c3202
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ISSN
1757-4676,1757-4684
E-ISSN
1757-4684
DOI
10.15252/emmm.202215821
