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Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened a...

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_363e13eead5c48ac8e3b452d2edf8f55

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

About this item

Full title

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Publisher

England: BioMed Central Ltd

Journal title

Journal of biology (London, England), 2002-11, Vol.1 (2), p.10-10, Article 10

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The Hedgehog (Hh) signaling pathway is vital to animal development as it mediates the differentiation of multiple cell types during embryogenesis. In adults, Hh signaling can be activated to facilitate tissue maintenance and repair. Moreover, stimulation of the Hh pathway has shown therapeutic efficacy in models of neuropathy. The underlying mechan...

Alternative Titles

Full title

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_363e13eead5c48ac8e3b452d2edf8f55

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_363e13eead5c48ac8e3b452d2edf8f55

Other Identifiers

ISSN

1475-4924,1478-5854

E-ISSN

1475-4924

DOI

10.1186/1475-4924-1-10

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