Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened a...
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The Hedgehog (Hh) signaling pathway is vital to animal development as it mediates the differentiation of multiple cell types during embryogenesis. In adults, Hh signaling can be activated to facilitate tissue maintenance and repair. Moreover, stimulation of the Hh pathway has shown therapeutic efficacy in models of neuropathy. The underlying mechan...
Alternative Titles
Full title
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_363e13eead5c48ac8e3b452d2edf8f55
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_363e13eead5c48ac8e3b452d2edf8f55
Other Identifiers
ISSN
1475-4924,1478-5854
E-ISSN
1475-4924
DOI
10.1186/1475-4924-1-10