PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
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Cambridge: eLife Sciences Publications Ltd
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English
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Cambridge: eLife Sciences Publications Ltd
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We recently reported that the inward-rectifier Kir2.1 channel in brain capillary endothelial cells (cECs) plays a major role in neurovascular coupling (NVC) by mediating a neuronal activity-dependent, propagating vasodilatory (hyperpolarizing) signal. We further demonstrated that Kir2.1 activity is suppressed by depletion of plasma membrane phospha...
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PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
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TN_cdi_doaj_primary_oai_doaj_org_article_36a3959b2839416b96d944daee300602
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36a3959b2839416b96d944daee300602
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.38689
