Tumor mutational burden assessment and standardized bioinformatics approach using custom NGS panels...
Tumor mutational burden assessment and standardized bioinformatics approach using custom NGS panels in clinical routine
About this item
Full title
Author / Creator
Dupain, Célia , Gutman, Tom , Girard, Elodie , Kamoun, Choumouss , Marret, Grégoire , Castel-Ajgal, Zahra , Sablin, Marie-Paule , Neuzillet, Cindy , Borcoman, Edith , Hescot, Ségolène , Callens, Céline , Trabelsi-Grati, Olfa , Melaabi, Samia , Vibert, Roseline , Antonio, Samantha , Franck, Coralie , Galut, Michèle , Guillou, Isabelle , Halladjian, Maral , Allory, Yves , Cyrta, Joanna , Romejon, Julien , Frouin, Eleonore , Stoppa-Lyonnet, Dominique , Wong, Jennifer , Le Tourneau, Christophe , Bièche, Ivan , Servant, Nicolas , Kamal, Maud and Masliah-Planchon, Julien
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
High tumor mutational burden (TMB) was reported to predict the efficacy of immune checkpoint inhibitors (ICIs). Pembrolizumab, an anti-PD-1, received FDA-approval for the treatment of unresectable/metastatic tumors with high TMB as determined by the FoundationOne®CDx test. It remains to be determined how TMB can also be calculated using other tests...
Alternative Titles
Full title
Tumor mutational burden assessment and standardized bioinformatics approach using custom NGS panels in clinical routine
Authors, Artists and Contributors
Author / Creator
Gutman, Tom
Girard, Elodie
Kamoun, Choumouss
Marret, Grégoire
Castel-Ajgal, Zahra
Sablin, Marie-Paule
Neuzillet, Cindy
Borcoman, Edith
Hescot, Ségolène
Callens, Céline
Trabelsi-Grati, Olfa
Melaabi, Samia
Vibert, Roseline
Antonio, Samantha
Franck, Coralie
Galut, Michèle
Guillou, Isabelle
Halladjian, Maral
Allory, Yves
Cyrta, Joanna
Romejon, Julien
Frouin, Eleonore
Stoppa-Lyonnet, Dominique
Wong, Jennifer
Le Tourneau, Christophe
Bièche, Ivan
Servant, Nicolas
Kamal, Maud
Masliah-Planchon, Julien
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_38a817e5035043189c5b339051b10be7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38a817e5035043189c5b339051b10be7
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-024-01839-8
