Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Org...
Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases
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Author / Creator
Sundstrom, Jonathan , Vanderleeden, Emma , Barton, Nathaniel J , Redick, Sambra D , Dawes, Pepper , Murray, Liam F , Olson, Meagan N , Tran, Khanh , Chigas, Samantha M , Orszulak, Adrian R , Church, George M , Readhead, Benjamin , Oh, Hyung Suk , Harlan, David M , Knipe, David M , Wang, Jennifer P , Chan, Yingleong and Lim, Elaine T
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Viral infections leading to inflammation have been implicated in several common diseases, such as Alzheimer's disease (AD) and type 1 diabetes (T1D). Of note, herpes simplex virus 1 (HSV-1) has been reported to be associated with AD. We sought to identify the transcriptomic changes due to HSV-1 infection and anti-viral drug (acyclovir, ACV) treatme...
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Full title
Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3b3add34bc8e44acbd5c612c96c50812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b3add34bc8e44acbd5c612c96c50812
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells13231978
