EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA for...
EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA formation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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eccDNA is a driver of many cancers and a potential intermediate in other age-related disorders. However, little is known about the mechanisms underlying eccDNA formation in healthy tissue and how aging affects these processes. Here, we present an atlas of eccDNA across seven tissues of male mice spanning four ages. EccDNA correlates with open chrom...
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EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA formation
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TN_cdi_doaj_primary_oai_doaj_org_article_3db2a1f82749430dabdcbff297918395
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3db2a1f82749430dabdcbff297918395
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57042-y