Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer ris...
Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer risk in BRCA1-positive women
About this item
Full title
Author / Creator
Sepahi, Ilnaz , Faust, Ulrike , Sturm, Marc , Bosse, Kristin , Kehrer, Martin , Heinrich, Tilman , Grundman-Hauser, Kathrin , Bauer, Peter , Ossowski, Stephan , Susak, Hana , Varon, Raymonda , Schröck, Evelin , Niederacher, Dieter , Auber, Bernd , Sutter, Christian , Arnold, Norbert , Hahnen, Eric , Dworniczak, Bernd , Wang-Gorke, Shan , Gehrig, Andrea , Weber, Bernhard H F , Engel, Christoph , Lemke, Johannes R , Hartkopf, Andreas , Nguyen, Huu Phuc , Riess, Olaf and Schroeder, Christopher
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Inherited pathogenic variants in BRCA1 and BRCA2 are the most common causes of hereditary breast and ovarian cancer (HBOC). The risk of developing breast cancer by age 80 in women carrying a BRCA1 pathogenic variant is 72%. The lifetime risk varies between families and even within affected individuals of the same family. The cause of this variabili...
Alternative Titles
Full title
Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer risk in BRCA1-positive women
Authors, Artists and Contributors
Author / Creator
Faust, Ulrike
Sturm, Marc
Bosse, Kristin
Kehrer, Martin
Heinrich, Tilman
Grundman-Hauser, Kathrin
Bauer, Peter
Ossowski, Stephan
Susak, Hana
Varon, Raymonda
Schröck, Evelin
Niederacher, Dieter
Auber, Bernd
Sutter, Christian
Arnold, Norbert
Hahnen, Eric
Dworniczak, Bernd
Wang-Gorke, Shan
Gehrig, Andrea
Weber, Bernhard H F
Engel, Christoph
Lemke, Johannes R
Hartkopf, Andreas
Nguyen, Huu Phuc
Riess, Olaf
Schroeder, Christopher
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3ef5711bdd6a4d41a69af27397cb98dc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ef5711bdd6a4d41a69af27397cb98dc
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-019-5946-0
