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Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of non...

Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of non...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48f02766cbcf45fab8fa2795bb729a58

Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

About this item

Full title

Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-03, Vol.9 (1), p.1203-9, Article 1203

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cell-free protein synthesis has emerged as a powerful approach for expanding the range of genetically encoded chemistry into proteins. Unfortunately, efforts to site-specifically incorporate multiple non-canonical amino acids into proteins using crude extract-based cell-free systems have been limited by release factor 1 competition. Here we address...

Alternative Titles

Full title

Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_48f02766cbcf45fab8fa2795bb729a58

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48f02766cbcf45fab8fa2795bb729a58

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03469-5

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