SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic...
SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart
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Author / Creator
Li, Chenguang , Zhang, Jie , Xue, Mei , Li, Xiaoyu , Han, Fei , Liu, Xiangyang , Xu, Linxin , Lu, Yunhong , Cheng, Ying , Li, Ting , Yu, Xiaochen , Sun, Bei and Chen, Liming
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Hyperglycaemia associated with myocardial oxidative stress and fibrosis is the main cause of diabetic cardiomyopathy. Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor has recently been reported to improve glycaemic control in patients with type 2 diabetes in an insulin-independent manner. The aim of this study was to investigate th...
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Full title
SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart
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TN_cdi_doaj_primary_oai_doaj_org_article_4ba6523e673b443a95b9427ec8314d14
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ba6523e673b443a95b9427ec8314d14
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ISSN
1475-2840
E-ISSN
1475-2840
DOI
10.1186/s12933-019-0816-2