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ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐...

ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_556a4cd04382499f8d2f42cfec59e8e5

ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐1‐dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

About this item

Full title

ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐1‐dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2018-10, Vol.12 (10), p.1735-1752

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

At the time of diagnosis, 20% of patients with colorectal cancer present metastasis. Among individuals with primary lesions, 50% of them will develop distant tumours with time. Therefore, early diagnosis and prediction of aggressiveness is crucial for therapy design and disease prognosis. Tumoral cells must undergo significant changes in energy met...

Alternative Titles

Full title

ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin‐1‐dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_556a4cd04382499f8d2f42cfec59e8e5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_556a4cd04382499f8d2f42cfec59e8e5

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1002/1878-0261.12367

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