Rifampin phosphotransferase is an unusual antibiotic resistance kinase
Rifampin phosphotransferase is an unusual antibiotic resistance kinase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Rifampin (RIF) phosphotransferase (RPH) confers antibiotic resistance by conversion of RIF and ATP, to inactive phospho-RIF, AMP and P
i
. Here we present the crystal structure of RPH from
Listeria monocytogenes
(RPH-
Lm
), which reveals that the enzyme is comprised of three domains: two substrate-binding domains (ATP-grasp and RI...
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Full title
Rifampin phosphotransferase is an unusual antibiotic resistance kinase
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TN_cdi_doaj_primary_oai_doaj_org_article_64b0a2b6d6ba4b86bd0e1b03eb366200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64b0a2b6d6ba4b86bd0e1b03eb366200
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11343
