Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albi...
Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Candida albicans
is the most common cause of life-threatening fungal infection in the developed world but remains a therapeutic challenge. Protein kinases have been rewarding drug targets across diverse indications but remain untapped for antifungal development. Previously, screening kinase inhibitors against
C. albicans
revealed a 2,3-ary...
Alternative Titles
Full title
Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_746af135086e4ba09862bfc8d373c3ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_746af135086e4ba09862bfc8d373c3ab
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57346-z
