The molecular basis for SARS-CoV-2 binding to dog ACE2
The molecular basis for SARS-CoV-2 binding to dog ACE2
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Author / Creator
Zhang, Zengyuan , Zhang, Yanfang , Liu, Kefang , Li, Yan , Lu, Qiong , Wang, Qingling , Zhang, Yuqin , Wang, Liang , Liao, Hanyi , Zheng, Anqi , Ma, Sufang , Fan, Zheng , Li, Huifang , Huang, Weijin , Bi, Yuhai , Zhao, Xin , Wang, Qihui , Gao, George F. , Xiao, Haixia , Tong, Zhou , Qi, Jianxun and Sun, Yeping
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
SARS-CoV-2 can infect many domestic animals, including dogs. Herein, we show that dog angiotensin-converting enzyme 2 (dACE2) can bind to the SARS-CoV-2 spike (S) protein receptor binding domain (RBD), and that both pseudotyped and authentic SARS-CoV-2 can infect dACE2-expressing cells. We solved the crystal structure of RBD in complex with dACE2 a...
Alternative Titles
Full title
The molecular basis for SARS-CoV-2 binding to dog ACE2
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_79fdbab038eb40bfba09615269e6e989
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_79fdbab038eb40bfba09615269e6e989
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24326-y
