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Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lympho...

Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lympho...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7fee3de7cd6b4b10b237a1df0b62b1d6

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

KMT2A
-rearranged infant acute lymphoblastic leukemia (ALL) represents the most refractory type of childhood leukemia. To uncover the molecular heterogeneity of this disease, we perform RNA sequencing, methylation array analysis, whole exome and targeted deep sequencing on 84 infants with
KMT2A
-rearranged leukemia. Our multi-omics cluster...

Alternative Titles

Full title

Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7fee3de7cd6b4b10b237a1df0b62b1d6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7fee3de7cd6b4b10b237a1df0b62b1d6

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-32266-4

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