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SLPI is a critical mediator that controls PTH-induced bone formation

SLPI is a critical mediator that controls PTH-induced bone formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80eb5385981346dea70479fd2d735e0d

SLPI is a critical mediator that controls PTH-induced bone formation

About this item

Full title

SLPI is a critical mediator that controls PTH-induced bone formation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-04, Vol.12 (1), p.2136-14, Article 2136

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Osteoclastic bone resorption and osteoblastic bone formation/replenishment are closely coupled in bone metabolism. Anabolic parathyroid hormone (PTH), which is commonly used for treating osteoporosis, shifts the balance from osteoclastic to osteoblastic, although it is unclear how these cells are coordinately regulated by PTH. Here, we identify a s...

Alternative Titles

Full title

SLPI is a critical mediator that controls PTH-induced bone formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_80eb5385981346dea70479fd2d735e0d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_80eb5385981346dea70479fd2d735e0d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22402-x

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