Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living...
Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells
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England: eLife Science Publications, Ltd
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Language
English
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England: eLife Science Publications, Ltd
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G protein-coupled receptors (GPCRs) signal through allostery, and it is increasingly clear that chemically distinct agonists can produce different receptor-based effects. It has been proposed that agonists selectively promote receptors to recruit one cellular interacting partner over another, introducing allosteric 'bias' into the signaling system....
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Full title
Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells
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TN_cdi_doaj_primary_oai_doaj_org_article_8c895244c98b40adb73cdb12ae8fea95
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c895244c98b40adb73cdb12ae8fea95
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.54208
