Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-...
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE)
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Author / Creator
Salloway, Stephen , Honigberg, Lee A , Cho, William , Ward, Michael , Friesenhahn, Michel , Brunstein, Flavia , Quartino, Angelica , Clayton, David , Mortensen, Deborah , Bittner, Tobias , Ho, Carole , Rabe, Christina , Schauer, Stephen P , Wildsmith, Kristin R , Fuji, Reina N , Suliman, Shehnaaz , Reiman, Eric M , Chen, Kewei and Paul, Robert
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of amyloid pathology, neurodegeneration, and disease progression in patients with mild-to-moderate Alzheimer's disease (AD).
This double-blind, placebo-controlled, randomized phase II study enrolled patients with...
Alternative Titles
Full title
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE)
Authors, Artists and Contributors
Author / Creator
Honigberg, Lee A
Cho, William
Ward, Michael
Friesenhahn, Michel
Brunstein, Flavia
Quartino, Angelica
Clayton, David
Mortensen, Deborah
Bittner, Tobias
Ho, Carole
Rabe, Christina
Schauer, Stephen P
Wildsmith, Kristin R
Fuji, Reina N
Suliman, Shehnaaz
Reiman, Eric M
Chen, Kewei
Paul, Robert
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a311ee7ca9264e6696bffa8520f93ab9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a311ee7ca9264e6696bffa8520f93ab9
Other Identifiers
ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-018-0424-5
