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ArticlesPeer ReviewedFull Text
Current state of Alzheimer’s fluid biomarkers
Author / Creator:Molinuevo, José Luis ; Ayton, Scott ; Batrla, Richard ; Bednar, Martin M. ; Bittner, Tobias ; Cummings, Jeffrey ; Fagan, Anne M. ; Hampel, Harald ; Mielke, Michelle M. ; Mikulskis, Alvydas ; O’Bryant, Sid ; Scheltens, Philip ; Sevigny, Jeffrey ; Shaw, Leslie M. ; Soares, Holly D. ; Tong, Gary ; Trojanowski, John Q. ; Zetterberg, Henrik ; Blennow, Kaj
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2018-12, Vol.136 (6), p.821-853
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Preanalytical sample handling recommendations for Alzheimer's disease plasma biomarkers
Author / Creator:Rózga, Małgorzata ; Bittner, Tobias ; Batrla, Richard ; Karl, Johann
Publisher:United States: Elsevier Inc
Journal title:Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2019-12, Vol.11 (1), p.291-300
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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
Author / Creator:Fuhrmann, Martin ; Bittner, Tobias ; Jung, Christian K E ; Burgold, Steffen ; Page, Richard M ; Mitteregger, Gerda ; Haass, Christian ; LaFerla, Frank M ; Kretzschmar, Hans ; Herms, Jochen
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2010-04, Vol.13 (4), p.411-413
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Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzhei...
Author / Creator:Salloway, Stephen ; Honigberg, Lee A ; Cho, William ; Ward, Michael ; Friesenhahn, Michel ; Brunstein, Flavia ; Quartino, Angelica ; Clayton, David ; Mortensen, Deborah ; Bittner, Tobias ; Ho, Carole ; Rabe, Christina ; Schauer, Stephen P ; Wildsmith, Kristin R ; Fuji, Reina N ; Suliman, Shehnaaz ; Reiman, Eric M ; Chen, Kewei ; Paul, Robert
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2018-09, Vol.10 (1), p.96-96, Article 96
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Blood‐based biomarkers for Alzheimer's pathology and the diagnostic process for a disease‐modifying treatment: Projecting the impact on the cost and wait times
Author / Creator:Mattke, Soeren ; Cho, Sang Kyu ; Bittner, Tobias ; Hlávka, Jakub ; Hanson, Mark
Publisher:United States: John Wiley & Sons, Inc
Journal title:Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2020, Vol.12 (1), p.e12081-n/a
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Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer's disease
Author / Creator:Yoshida, Kenta ; Moein, Anita ; Bittner, Tobias ; Ostrowitzki, Susanne ; Lin, Helen ; Honigberg, Lee ; Jin, Jin Y ; Quartino, Angelica
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2020-01, Vol.12 (1), p.16-12, Article 16
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Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice
Author / Creator:Bittner, Tobias ; Fuhrmann, Martin ; Burgold, Steffen ; Ochs, Simon M ; Hoffmann, Nadine ; Mitteregger, Gerda ; Kretzschmar, Hans ; LaFerla, Frank M ; Herms, Jochen
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-11, Vol.5 (11), p.e15477
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Identifying clinically useful biomarkers in neurodegenerative disease through a collaborative approach: the NeuroToolKit
Author / Creator:Johnson, Sterling C ; Suárez-Calvet, Marc ; Suridjan, Ivonne ; Minguillón, Carolina ; Gispert, Juan Domingo ; Jonaitis, Erin ; Michna, Agata ; Carboni, Margherita ; Bittner, Tobias ; Rabe, Christina ; Kollmorgen, Gwendlyn ; Zetterberg, Henrik ; Blennow, Kaj
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2023-01, Vol.15 (1), p.25-25, Article 25
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Blood‐based biomarkers and risk of MCI symptom onset over the short and long‐term
Author / Creator:Soldan, Anja ; Pettigrew, Corinne ; Wang, Jiangxia ; Albert, Marilyn S. ; Blennow, Kaj ; Bittner, Tobias ; Moghekar, Abhay
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S2), p.n/a
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Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal fluid
Author / Creator:Leinenbach, Andreas ; Pannee, Josef ; Dülffer, Thomas ; Huber, Andreas ; Bittner, Tobias ; Andreasson, Ulf ; Gobom, Johan ; Zetterberg, Henrik ; Kobold, Uwe ; Portelius, Erik ; Blennow, Kaj
Publisher:England
Journal title:Clinical chemistry (Baltimore, Md.), 2014-07, Vol.60 (7), p.987-994
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Plasma biomarker trajectories: Relationship to AD genetic risk factors among cognitively unimpaired individuals
Author / Creator:Pettigrew, Corinne ; Wang, Jiangxia ; Soldan, Anja ; Hohman, Timothy J. ; Dumitrescu, Logan C. ; Wang, Mei‐Cheng ; Albert, Marilyn S. ; Blennow, Kaj ; Bittner, Tobias ; Moghekar, Abhay
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S2), p.n/a
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052 SKYLINE study design efficacy and safety of gantenerumab in participants at-risk for Alzheimer’s disease
Author / Creator:Bullain, Szofia ; Delmar, Paul ; Sperling, Reisa ; Reiman, Eric M ; Aisen, Paul ; Wojtowicz, Jakub ; Bittner, Tobias ; Ashford, Elizabeth ; Doody, Rachelle S ; Ostrowitzki, Susanne
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal of neurology, neurosurgery and psychiatry, 2022-09, Vol.93 (9), p.e2
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Biomarker treatment effects in two phase 3 trials of gantenerumab
Author / Creator:Bittner, Tobias ; Tonietto, Matteo ; Klein, Gregory ; Belusov, Anton ; Illiano, Vittorio ; Voyle, Nicola ; Delmar, Paul ; Scelsi, Marzia A. ; Gobbi, Susanna ; Silvestri, Erica ; Barakovic, Muhamed ; Napolitano, Antonio ; Galli, Christopher ; Abaei, Maryam ; Blennow, Kaj ; Barkhof, Frederik
Publisher:United States: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2025-01, Vol.21 (2), p.e14414-n/a
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ArticlesPeer ReviewedFull Text
Amyloid plaque formation precedes dendritic spine loss
Author / Creator:Bittner, Tobias ; Burgold, Steffen ; Dorostkar, Mario M. ; Fuhrmann, Martin ; Wegenast-Braun, Bettina M. ; Schmidt, Boris ; Kretzschmar, Hans ; Herms, Jochen
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Acta neuropathologica, 2012-12, Vol.124 (6), p.797-807
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Impact of gantenerumab amyloid removal therapy on established Alzheimer Disease fluid biomarkers
Author / Creator:Ibanez, Laura ; Li, Yan ; McDade, Eric ; Llibre‐Guerra, Jorge J. ; Clifford, David B. ; Mills, Susan ; Santacruz, Anna ; Wang, Guoqiao ; Supnet‐Bell, Charlene ; Benzinger, Tammie L.S. ; Gordon, Brian A. ; Klein, Gregory ; Baudler, Monika ; Doody, Rachelle S. ; Kerchner, Geoffrey A. ; Bittner, Tobias ; Atri, Alireza ; Bateman, Randall J.
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S8), p.n/a
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In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks
Author / Creator:Burgold, Steffen ; Bittner, Tobias ; Dorostkar, Mario M. ; Kieser, Daniel ; Fuhrmann, Martin ; Mitteregger, Gerda ; Kretzschmar, Hans ; Schmidt, Boris ; Herms, Jochen
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Acta neuropathologica, 2011-03, Vol.121 (3), p.327-335
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The global Alzheimer's Association round robin study on plasma amyloid β methods
Author / Creator:Pannee, Josef ; Shaw, Leslie M. ; Korecka, Magdalena ; Waligorska, Teresa ; Teunissen, Charlotte E. ; Stoops, Erik ; Vanderstichele, Hugo M. J. ; Mauroo, Kimberley ; Verberk, Inge M. W. ; Keshavan, Ashvini ; Pesini, Pedro ; Sarasa, Leticia ; Pascual‐Lucas, Maria ; Fandos, Noelia ; Allué, José‐Antonio ; Portelius, Erik ; Andreasson, Ulf ; Yoda, Ritsuko ; Nakamura, Akinori ; Kaneko, Naoki ; Yang, Shieh‐Yueh ; Liu, Huei‐Chun ; Palme, Stefan ; Bittner, Tobias ; Mawuenyega, Kwasi G. ; Ovod, Vitaliy ; Bollinger, James ; Bateman, Randall J. ; Li, Yan ; Dage, Jeffrey L. ; Stomrud, Erik ; Hansson, Oskar ; Schott, Jonathan M. ; Blennow, Kaj ; Zetterberg, Henrik
Publisher:United States: John Wiley & Sons, Inc
Journal title:Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2021, Vol.13 (1), p.e12242-n/a
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Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease
Author / Creator:Wang, Guoqiao ; Li, Yan ; Xiong, Chengjie ; Benzinger, Tammie L. S. ; Gordon, Brian A. ; Hassenstab, Jason ; Aschenbrenner, Andrew J. ; McDade, Eric ; Clifford, David B. ; Libre‐Guerra, Jorge J. ; Shi, Xinyu ; Mummery, Catherine J. ; Dyck, Christopher H. ; Lah, James J. ; Honig, Lawrence S. ; Day, Gregg ; Ringman, John M. ; Brooks, William S. ; Fox, Nick C. ; Suzuki, Kazushi ; Levin, Johannes ; Jucker, Mathias ; Delmar, Paul ; Bittner, Tobias ; Bateman, Randall J.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Alzheimer's & dementia, 2024-04, Vol.20 (4), p.2698-2706
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ArticlesPeer ReviewedFull Text
Mass Spectrometry-Based Candidate Reference Measurement Procedure for Quantification of Amyloid-[Beta] in Cerebrospinal Fluid
Author / Creator:Leinenbach, Andreas ; Pannee, Josef ; Dülffer, Thomas ; Huber, Andreas ; Bittner, Tobias ; Andreasson, Ulf ; Gobom, Johan ; Zetterberg, Henrik ; Kobold, Uwe ; Portelius, Erik ; Blennow, Kaj
Publisher:Washington: Oxford University Press
Journal title:Clinical chemistry (Baltimore, Md.), 2014-07, Vol.60 (7), p.987
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Evaluation of dose‐dependent treatment effects after mid‐trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's diseas...
Author / Creator:Wang, Guoqiao ; Li, Yan ; Xiong, Chengjie ; McDade, Eric ; Clifford, David B. ; Mills, Susan L. ; Santacruz, Anna M. ; Aschenbrenner, Andrew J. ; Hassenstab, Jason ; Benzinger, Tammie L.S. ; Gordon, Brian A. ; Fagan, Anne M. ; Coalier, Kelley A. ; Libre‐Guerra, Jorge J. ; McCullough, Austin ; Joseph‐Mathurin, Nelly ; Chen, Charles D. ; Mummery, Catherine ; Wendelberger, Barbara A. ; Gauthier, Serge ; Masellis, Mario ; Holdridge, Karen C. ; Yaari, Roy ; Chatterjee, Saptarshi ; Sims, John ; Delmar, Paul ; Kerchner, Geoffrey A. ; Bittner, Tobias ; Hofmann, Carsten ; Bateman, Randall J.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2022, Vol.14 (1), p.e12367-n/a
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Current state of Alzheimer’s fluid biomarkers

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Preanalytical sample handling recommendations for Alzheimer's disease plasma biomarkers

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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

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Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzhei...

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Blood‐based biomarkers for Alzheimer's pathology and the diagnostic process for a disease‐modifying treatment: Projecting the impact on the cost and wait times

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Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer's disease

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Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice

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Identifying clinically useful biomarkers in neurodegenerative disease through a collaborative approach: the NeuroToolKit

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Blood‐based biomarkers and risk of MCI symptom onset over the short and long‐term

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Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal fluid

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Plasma biomarker trajectories: Relationship to AD genetic risk factors among cognitively unimpaired individuals

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052 SKYLINE study design efficacy and safety of gantenerumab in participants at-risk for Alzheimer’s disease

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Biomarker treatment effects in two phase 3 trials of gantenerumab

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Amyloid plaque formation precedes dendritic spine loss

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Impact of gantenerumab amyloid removal therapy on established Alzheimer Disease fluid biomarkers

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In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

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The global Alzheimer's Association round robin study on plasma amyloid β methods

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Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease

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Mass Spectrometry-Based Candidate Reference Measurement Procedure for Quantification of Amyloid-[Beta] in Cerebrospinal Fluid

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Evaluation of dose‐dependent treatment effects after mid‐trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's diseas...

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