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MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine inse...

MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine inse...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66019571d8948dc99880c2ec77b29dc

MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity

About this item

Full title

MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2025-04, Vol.16 (1), p.268-14, Article 268

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Melanoma is among the 10 most prevalent malignant tumors, posing a significant threat to human health. A detailed understanding of the molecular mechanisms driving its progression is crucial for advancing treatment strategies and outcomes. Based on bioinformatic analysis and experimental validation, this study identified mitochondrial carrier homol...

Alternative Titles

Full title

MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a66019571d8948dc99880c2ec77b29dc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66019571d8948dc99880c2ec77b29dc

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-025-07618-9

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