MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine inse...
MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity
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Author / Creator
Zhang, Xuedan , Li, Enjiang , Kuang, Yingmin , Gai, Yanlong , Feng, Yu , Huang, Yu , Wei, Zhenyan , Niu, Junzi , Yu, Song , Yang, Zhe , Zhang, Qiao , Sai, Buqing and Zhu, Yuechun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Melanoma is among the 10 most prevalent malignant tumors, posing a significant threat to human health. A detailed understanding of the molecular mechanisms driving its progression is crucial for advancing treatment strategies and outcomes. Based on bioinformatic analysis and experimental validation, this study identified mitochondrial carrier homol...
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Full title
MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a66019571d8948dc99880c2ec77b29dc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66019571d8948dc99880c2ec77b29dc
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-025-07618-9