Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule...
Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain development is unknown. In this study, we show that mouse Sema5A negatively regulates synaptogenesis in early, developmentally born, hippocampal dentate granule cells (GCs). Sema5A is strongly expressed by GCs and regulates dendritic spine density in a cel...
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Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells
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TN_cdi_doaj_primary_oai_doaj_org_article_a9f0fce5f614463ea6faa85d10e7d2b0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9f0fce5f614463ea6faa85d10e7d2b0
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.04390
