The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabi...
The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
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Author / Creator
Wang, Xia , Ji, Yuge , Feng, Panpan , Liu, Rucheng , Li, Guosheng , Zheng, Junjie , Xue, Yaqiang , Wei, Yaxun , Ji, Chunyan , Chen, Dawei and Li, Jingxin
Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment. Currently, little is known about how the intrinsic regulators modulate proinflammatory (M1) versus prohealing (M2) macrophages activation. Here, it is observed that insulin‐like growth factor 2 messenger RNA (mRNA)‐binding protein 2 (IGF2BP...
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Full title
The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
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TN_cdi_doaj_primary_oai_doaj_org_article_be727d87a7bb4484b459fc66c0bb3e64
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be727d87a7bb4484b459fc66c0bb3e64
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202100209