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ArticlesPeer ReviewedFull Text
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
Author / Creator:Tsai, Peter T. ; Hull, Court ; Chu, YunXiang ; Greene-Colozzi, Emily ; Sadowski, Abbey R. ; Leech, Jarrett M. ; Steinberg, Jason ; Crawley, Jacqueline N. ; Regehr, Wade G. ; Sahin, Mustafa
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-08, Vol.488 (7413), p.647-651
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Tsc1 promotes the differentiation of memory CD8⁺ T cells via orchestrating the transcriptional and metabolic programs
Author / Creator:Shrestha, Sharad ; Yang, Kai ; Wei, Jun ; Karmaus, Peer W. F. ; Neale, Geoffrey ; Chi, Hongbo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14858-14863
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Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
Author / Creator:Papadakis, Michalis ; Hadley, Gina ; Xilouri, Maria ; Hoyte, Lisa C ; Nagel, Simon ; McMenamin, M Mary ; Tsaknakis, Grigorios ; Watt, Suzanne M ; Drakesmith, Cynthia Wright ; Chen, Ruoli ; Wood, Matthew J A ; Zhao, Zonghang ; Kessler, Benedikt ; Vekrellis, Kostas ; Buchan, Alastair M
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2013-03, Vol.19 (3), p.351-357
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Role of TSC1 in physiology and diseases
Author / Creator:Mallela, Karthik ; Kumar, Arun
Publisher:New York: Springer US
Journal title:Molecular and cellular biochemistry, 2021-06, Vol.476 (6), p.2269-2282
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TSC1 controls macrophage polarization to prevent inflammatory disease
Author / Creator:Zhu, Linnan ; Yang, Tao ; Li, Longjie ; Sun, Lina ; Hou, Yuzhu ; Hu, Xuelian ; Zhang, Lianjun ; Tian, Hongling ; Zhao, Qingjie ; Peng, Jianxia ; Zhang, Hongbing ; Wang, Ruoyu ; Yang, Zhongzhou ; Zhang, Lianfeng ; Zhao, Yong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-09, Vol.5 (1), p.4696-4696, Article 4696
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Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer
Author / Creator:Xie, Yadong ; Zhao, Yifan ; Shi, Lei ; Li, Wei ; Chen, Kun ; Li, Min ; Chen, Xia ; Zhang, Haiwei ; Li, Tiantian ; Matsuzawa-Ishimoto, Yu ; Yao, Xiaomin ; Shao, Dianhui ; Ke, Zunfu ; Li, Jian ; Chen, Yan ; Zhang, Xiaoming ; Cui, Jun ; Cui, Shuzhong ; Leng, Qibin ; Cadwell, Ken ; Li, Xiaoxia ; Wei, Hong ; Zhang, Haibing ; Li, Huabin ; Xiao, Hui
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-04, Vol.130 (4), p.2111-2128
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Tsc1 regulates tight junction independent of mTORC1
Author / Creator:Lai, Mingqiang ; Zou, Wenchong ; Han, Zelong ; Zhou, Ling ; Qiu, Zeyou ; Chen, Juan ; Zhang, Sheng ; Lai, Pinglin ; Li, Kai ; Zhang, Yue ; Liang, Li ; Jiang, Yu ; Zou, Zhipeng ; Bai, Xiaochun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30), p.1-12
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A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model
Author / Creator:Wesseling, Hendrik ; Elgersma, Ype ; Bahn, Sabine
Publisher:England: BioMed Central Ltd
Journal title:Molecular autism, 2017-08, Vol.8 (1), p.41-41, Article 41
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The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
Author / Creator:Wang, Xia ; Ji, Yuge ; Feng, Panpan ; Liu, Rucheng ; Li, Guosheng ; Zheng, Junjie ; Xue, Yaqiang ; Wei, Yaxun ; Ji, Chunyan ; Chen, Dawei ; Li, Jingxin
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2021-07, Vol.8 (13), p.2100209-n/a
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Variants of TSC1 are associated with developmental and epileptic encephalopathy and focal epilepsy without tuberous sclerosis: For the China Epilepsy Gene 1.0 Project
Author / Creator:Shen, Nanxiang ; Zhuo, Zhihong ; Luo, Xiangyun ; Li, Bingmei ; Lin, Xuqing ; Luo, Sheng ; Ye, Zilong ; Wang, Pengyu ; He, Na ; Shi, Yiwu ; Liao, Weiping
Publisher:England: BioMed Central
Journal title:Acta epileptologica, 2024-11, Vol.6 (1), p.41, Article 41
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The role of TSC1 and TSC2 proteins in neuronal axons
Author / Creator:Karalis, Vasiliki ; Wood, Delaney ; Teaney, Nicole A. ; Sahin, Mustafa
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2024-04, Vol.29 (4), p.1165-1178
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mTORC1 Activation in Chx10-Specific Tsc1 Knockout Mice Accelerates Retina Aging and Degeneration
Author / Creator:Rao, Yu-Qing ; Zhou, Yu-Tong ; Zhou, Wenchuan ; Li, Jia-Kai ; Li, Baojie ; Li, Jing
Publisher:United States: Hindawi
Journal title:Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.6715758-6715758
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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma
Author / Creator:Wang, Yuqiong ; Zhang, Xiyu ; Tang, Wei ; Lin, Zhenghong ; Xu, Limei ; Dong, Ruifen ; Li, Yinuo ; Li, Jieyin ; Zhang, Zaixin ; Li, Xiangzhi ; Zhao, Ling ; Wei, Jian-Jun ; Shao, Changshun ; Kong, Beihua ; Liu, Zhaojian
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-12, Vol.24 (12), p.2089-2100
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TSC1 regulates the balance between effector and regulatory T cells
Author / Creator:Park, Yoon ; Jin, Hyung-Seung ; Lopez, Justine ; Elly, Chris ; Kim, Gisen ; Murai, Masako ; Kronenberg, Mitchell ; Liu, Yun-Cai
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5165-5178
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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-[kappa]B in high-grade serous ovarian carcinoma
Author / Creator:Wang, Yuqiong ; Zhang, Xiyu ; Tang, Wei ; Lin, Zhenghong ; Xu, Limei ; Dong, Ruifen ; Li, Yinuo ; Li, Jieyin ; Zhang, Zaixin ; Li, Xiangzhi ; Zhao, Ling ; Wei, Jian-jun ; Shao, Changshun ; Kong, Beihua ; Liu, Zhaojian
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2017-12, Vol.24 (12), p.2089
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MiR‐451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1
Author / Creator:Song, Lei ; Su, Ming ; Wang, Shuiyun ; Zou, Yubao ; Wang, Xiaojian ; Wang, Yilu ; Cui, Hongli ; Zhao, Peng ; Hui, Rutai ; Wang, Jizheng
Publisher:England: BlackWell Publishing Ltd
Journal title:Journal of cellular and molecular medicine, 2014-11, Vol.18 (11), p.2266-2274
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miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1
Author / Creator:Chen, Yanting ; Li, Shanxiang ; He, Hong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.19353-12, Article 19353
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TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication
Author / Creator:Ho, Daniel W H ; Chan, Lo K ; Chiu, Yung T ; Xu, Iris M J ; Poon, Ronnie T P ; Cheung, Tan T ; Tang, Chung N ; Tang, Victor W L ; Lo, Irene L O ; Lam, Polly W Y ; Yau, Derek T W ; Li, Miao X ; Wong, Chun M ; Ng, Irene O L
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-08, Vol.66 (8), p.1496-1506
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Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing
Author / Creator:Tyburczy, Magdalena E. ; Dies, Kira A. ; Glass, Jennifer ; Camposano, Susana ; Chekaluk, Yvonne ; Thorner, Aaron R. ; Lin, Ling ; Krueger, Darcy ; Franz, David N. ; Thiele, Elizabeth A. ; Sahin, Mustafa ; Kwiatkowski, David J.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-11, Vol.11 (11), p.e1005637-e1005637
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Tackling Tsc1 to Promote Nephrogenesis
Author / Creator:Ingelfinger, Julie R
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-12, Vol.379 (25), p.2476-2478
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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

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Tsc1 promotes the differentiation of memory CD8⁺ T cells via orchestrating the transcriptional and metabolic programs

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Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

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Role of TSC1 in physiology and diseases

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TSC1 controls macrophage polarization to prevent inflammatory disease

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Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer

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Tsc1 regulates tight junction independent of mTORC1

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A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

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The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ

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Variants of TSC1 are associated with developmental and epileptic encephalopathy and focal epilepsy without tuberous sclerosis: For the China Epilepsy Gene 1.0 Project

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The role of TSC1 and TSC2 proteins in neuronal axons

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mTORC1 Activation in Chx10-Specific Tsc1 Knockout Mice Accelerates Retina Aging and Degeneration

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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma

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TSC1 regulates the balance between effector and regulatory T cells

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miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-[kappa]B in high-grade serous ovarian carcinoma

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MiR‐451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1

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miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1

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TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication

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Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing

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Tackling Tsc1 to Promote Nephrogenesis

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