Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neut...
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
About this item
Full title
Author / Creator
Fougeroux, Cyrielle , Goksøyr, Louise , Idorn, Manja , Soroka, Vladislav , Myeni, Sebenzile K. , Dagil, Robert , Janitzek, Christoph M. , Søgaard, Max , Aves, Kara-Lee , Horsted, Emma W. , Erdoğan, Sayit Mahmut , Gustavsson, Tobias , Dorosz, Jerzy , Clemmensen, Stine , Fredsgaard, Laurits , Thrane, Susan , Vidal-Calvo, Elena E. , Khalifé, Paul , Hulen, Thomas M. , Choudhary, Swati , Theisen, Michael , Singh, Susheel K. , Garcia-Senosiain, Asier , Van Oosten, Linda , Pijlman, Gorben , Hierzberger, Bettina , Domeyer, Tanja , Nalewajek, Blanka W. , Strøbæk, Anette , Skrzypczak, Magdalena , Andersson, Laura F. , Buus, Søren , Buus, Anette Stryhn , Christensen, Jan Pravsgaard , Dalebout, Tim J. , Iversen, Kasper , Harritshøj, Lene H. , Mordmüller, Benjamin , Ullum, Henrik , Reinert, Line S. , de Jongh, Willem Adriaan , Kikkert, Marjolein , Paludan, Søren R. , Theander, Thor G. , Nielsen, Morten A. , Salanti, Ali and Sander, Adam F.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The rapid development of a SARS-CoV-2 vaccine is a global priority. Here, we develop two capsid-like particle (CLP)-based vaccines displaying the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. RBD antigens are displayed on AP205 CLPs through a split-protein Tag/Catcher, ensuring unidirectional and high-density display of RBD. Both s...
Alternative Titles
Full title
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity
Authors, Artists and Contributors
Author / Creator
Goksøyr, Louise
Idorn, Manja
Soroka, Vladislav
Myeni, Sebenzile K.
Dagil, Robert
Janitzek, Christoph M.
Søgaard, Max
Aves, Kara-Lee
Horsted, Emma W.
Erdoğan, Sayit Mahmut
Gustavsson, Tobias
Dorosz, Jerzy
Clemmensen, Stine
Fredsgaard, Laurits
Thrane, Susan
Vidal-Calvo, Elena E.
Khalifé, Paul
Hulen, Thomas M.
Choudhary, Swati
Theisen, Michael
Singh, Susheel K.
Garcia-Senosiain, Asier
Van Oosten, Linda
Pijlman, Gorben
Hierzberger, Bettina
Domeyer, Tanja
Nalewajek, Blanka W.
Strøbæk, Anette
Skrzypczak, Magdalena
Andersson, Laura F.
Buus, Søren
Buus, Anette Stryhn
Christensen, Jan Pravsgaard
Dalebout, Tim J.
Iversen, Kasper
Harritshøj, Lene H.
Mordmüller, Benjamin
Ullum, Henrik
Reinert, Line S.
de Jongh, Willem Adriaan
Kikkert, Marjolein
Paludan, Søren R.
Theander, Thor G.
Nielsen, Morten A.
Salanti, Ali
Sander, Adam F.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c047e4469bfc4df49317bf7ddb5a7a95
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c047e4469bfc4df49317bf7ddb5a7a95
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20251-8
