IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-tr...
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
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Author / Creator
Harper, Justin , Huot, Nicolas , Micci, Luca , Tharp, Gregory , King, Colin , Rascle, Philippe , Shenvi, Neeta , Wang, Hong , Galardi, Cristin , Upadhyay, Amit A. , Villinger, Francois , Lifson, Jeffrey , Silvestri, Guido , Easley, Kirk , Jacquelin, Beatrice , Bosinger, Steven , Müller-Trutwin, Michaela and Paiardini, Mirko
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Unlike HIV infection, which progresses to AIDS absent suppressive anti-retroviral therapy, nonpathogenic infections in natural hosts, such African green monkeys, are characterized by a lack of gut microbial translocation and robust secondary lymphoid natural killer cell responses resulting in an absence of chronic inflammation and limited SIV disse...
Alternative Titles
Full title
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c2ab2bb398384c18b3ef628de01ccc2b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c2ab2bb398384c18b3ef628de01ccc2b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23189-7
