Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors
Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors
About this item
Full title
Author / Creator
Tanaka, Yosuke , Takeda, Reina , Fukushima, Tsuyoshi , Mikami, Keiko , Tsuchiya, Shun , Tamura, Moe , Adachi, Keito , Umemoto, Terumasa , Asada, Shuhei , Watanabe, Naoki , Morishita, Soji , Imai, Misa , Nagata, Masayoshi , Araki, Marito , Takizawa, Hitoshi , Fukuyama, Tomofusa , Lamagna, Chrystelle , Masuda, Esteban S. , Ito, Ryoji , Goyama, Susumu , Komatsu, Norio , Takaku, Tomoiku and Kitamura, Toshio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) are quiescent, insensitive to BCR-ABL1 tyrosine kinase inhibitors (TKIs) and responsible for CML relapse. Therefore, eradicating quiescent CML LSCs is a major goal in CML therapy. Here, using a G
0
marker (G
0
M), we narrow down CML LSCs as G
0
M- and CD27- double positi...
Alternative Titles
Full title
Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors
Authors, Artists and Contributors
Author / Creator
Takeda, Reina
Fukushima, Tsuyoshi
Mikami, Keiko
Tsuchiya, Shun
Tamura, Moe
Adachi, Keito
Umemoto, Terumasa
Asada, Shuhei
Watanabe, Naoki
Morishita, Soji
Imai, Misa
Nagata, Masayoshi
Araki, Marito
Takizawa, Hitoshi
Fukuyama, Tomofusa
Lamagna, Chrystelle
Masuda, Esteban S.
Ito, Ryoji
Goyama, Susumu
Komatsu, Norio
Takaku, Tomoiku
Kitamura, Toshio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c3477c962caf480e9537b3db7eabd49c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3477c962caf480e9537b3db7eabd49c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27928-8
