Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defect...
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
About this item
Full title
Author / Creator
Rosety, Isabel , Zagare, Alise , Saraiva, Claudia , Nickels, Sarah , Antony, Paul , Almeida, Catarina , Glaab, Enrico , Halder, Rashi , Velychko, Sergiy , Rauen, Thomas , Schöler, Hans R. , Bolognin, Silvia , Sauter, Thomas , Jarazo, Javier , Krüger, Rejko , Schwamborn, Jens C. and USDOE Yucca Mountain Site, Las Vegas, NV (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The mechanisms underlying Parkinson’s disease (PD) etiology are only partially understood despite intensive research conducted in the field. Recent evidence suggests that early neurodevelopmental defects might play a role in cellular susceptibility to neurodegeneration. To study the early developmental contribution of GBA mutations in PD we used pa...
Alternative Titles
Full title
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
Authors, Artists and Contributors
Author / Creator
Zagare, Alise
Saraiva, Claudia
Nickels, Sarah
Antony, Paul
Almeida, Catarina
Glaab, Enrico
Halder, Rashi
Velychko, Sergiy
Rauen, Thomas
Schöler, Hans R.
Bolognin, Silvia
Sauter, Thomas
Jarazo, Javier
Krüger, Rejko
Schwamborn, Jens C.
USDOE Yucca Mountain Site, Las Vegas, NV (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c8a751fed40447b48458240c44c2fae3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8a751fed40447b48458240c44c2fae3
Other Identifiers
ISSN
2373-8057
E-ISSN
2373-8057
DOI
10.1038/s41531-023-00616-8
