PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with...
PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance
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Full title
Author / Creator
Montaudon, Elodie , Nikitorowicz-Buniak, Joanna , Sourd, Laura , Morisset, Ludivine , El Botty, Rania , Huguet, Léa , Dahmani, Ahmed , Painsec, Pierre , Nemati, Fariba , Vacher, Sophie , Chemlali, Walid , Masliah-Planchon, Julien , Château-Joubert, Sophie , Rega, Camilla , Leal, Mariana Ferreira , Simigdala, Nikiana , Pancholi, Sunil , Ribas, Ricardo , Nicolas, André , Meseure, Didier , Vincent-Salomon, Anne , Reyes, Cécile , Rapinat, Audrey , Gentien, David , Larcher, Thibaut , Bohec, Mylène , Baulande, Sylvain , Bernard, Virginie , Decaudin, Didier , Coussy, Florence , Le Romancer, Muriel , Dutertre, Guillaume , Tariq, Zakia , Cottu, Paul , Driouch, Keltouma , Bièche, Ivan , Martin, Lesley-Ann and Marangoni, Elisabetta
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Here we perform whole exome sequencing and gene expression analysis of matched primary breast tumours and bone metastasis-derived patient-derived xenografts (PDX). Transc...
Alternative Titles
Full title
PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance
Authors, Artists and Contributors
Author / Creator
Nikitorowicz-Buniak, Joanna
Sourd, Laura
Morisset, Ludivine
El Botty, Rania
Huguet, Léa
Dahmani, Ahmed
Painsec, Pierre
Nemati, Fariba
Vacher, Sophie
Chemlali, Walid
Masliah-Planchon, Julien
Château-Joubert, Sophie
Rega, Camilla
Leal, Mariana Ferreira
Simigdala, Nikiana
Pancholi, Sunil
Ribas, Ricardo
Nicolas, André
Meseure, Didier
Vincent-Salomon, Anne
Reyes, Cécile
Rapinat, Audrey
Gentien, David
Larcher, Thibaut
Bohec, Mylène
Baulande, Sylvain
Bernard, Virginie
Decaudin, Didier
Coussy, Florence
Le Romancer, Muriel
Dutertre, Guillaume
Tariq, Zakia
Cottu, Paul
Driouch, Keltouma
Bièche, Ivan
Martin, Lesley-Ann
Marangoni, Elisabetta
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cbbadef41cb14a1b91639138a1f60fcb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cbbadef41cb14a1b91639138a1f60fcb
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17697-1
