Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac...
Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of β1 adrenergic receptors (βARs) on cardiac myocytes. Blocking these receptors is part of the basis for β-blocker therapy for heart failure. Recent data demonstrate that G protein-coupled receptors (GPCRs), inc...
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Full title
Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy
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TN_cdi_doaj_primary_oai_doaj_org_article_cd20c8c45b644356bdd01626b8b031de
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd20c8c45b644356bdd01626b8b031de
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.48167
