ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Mu...
ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK
About this item
Full title
Author / Creator
Jacobs, Benjamin M , Schalk, Luisa , Dunne, Angie , Scalfari, Antonio , Nandoskar, Ashwini , Gran, Bruno , Mein, Charles A , Sellers, Charlotte , Spilker, Cord , Rog, David , Visentin, Elisa , Bezzina, Elizabeth Lindsey , Uzochukwu, Emeka , Tallantyre, Emma , Wozniak, Eva , Sacre, Eve , Hassan-Smith, Ghaniah , Ford, Helen L , Harris, Jade , Bradley, Joan , Breedon, Joshua , Brooke, Judith , Kreft, Karim L , Tuite Dalton, Katherine , George, Katila , Papachatzaki, Maria , O'Malley, Martin , Peter, Michelle , Mattoscio, Miriam , Rhule, Neisha , Evangelou, Nikos , Vinod, Nimisha , Quinn, Outi , Shamji, Ramya , Kaimal, Rashmi , Boulton, Rebecca , Tanveer, Riffat , Middleton, Rod , Murray, Roxanne , Bellfield, Ruth , Hoque, Sadid , Patel, Shakeelah , Raj, Sonia , Gumus, Stephanie , Mitchell, Stephanie , Sawcer, Stephen , Arun, Tarunya , Pogreban, Tatiana , Brown, Terri-Louise , Begum, Thamanna , Antoine, Veronica , Rashid, Waqar , Noyce, Alastair J , Silber, Eli , Morris, Huw , Giovannoni, Gavin and Dobson, Ruth
Publisher
England: British Medical Journal Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
England: British Medical Journal Publishing Group
Subjects
More information
Scope and Contents
Contents
PurposeGenetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS) project aims to gather genetic and phenotypic data on a large cohort of ancestrally-diverse individuals with MS living in the UK.ParticipantsAdults with self-reported MS from diverse ancestral backgrounds. Recruitment is via clinical sites, online (https://app.mantal.co.uk/adams) or the UK MS Register. We are collecting demographic and phenotypic data using a baseline questionnaire and subsequent healthcare record linkage. We are collecting DNA from participants using saliva kits (Oragene-600) and genotyping using the Illumina Global Screening Array V.3.Findings to dateAs of 3 January 2023, we have recruited 682 parti...
Alternative Titles
Full title
ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK
Authors, Artists and Contributors
Author / Creator
Schalk, Luisa
Dunne, Angie
Scalfari, Antonio
Nandoskar, Ashwini
Gran, Bruno
Mein, Charles A
Sellers, Charlotte
Spilker, Cord
Rog, David
Visentin, Elisa
Bezzina, Elizabeth Lindsey
Uzochukwu, Emeka
Tallantyre, Emma
Wozniak, Eva
Sacre, Eve
Hassan-Smith, Ghaniah
Ford, Helen L
Harris, Jade
Bradley, Joan
Breedon, Joshua
Brooke, Judith
Kreft, Karim L
Tuite Dalton, Katherine
George, Katila
Papachatzaki, Maria
O'Malley, Martin
Peter, Michelle
Mattoscio, Miriam
Rhule, Neisha
Evangelou, Nikos
Vinod, Nimisha
Quinn, Outi
Shamji, Ramya
Kaimal, Rashmi
Boulton, Rebecca
Tanveer, Riffat
Middleton, Rod
Murray, Roxanne
Bellfield, Ruth
Hoque, Sadid
Patel, Shakeelah
Raj, Sonia
Gumus, Stephanie
Mitchell, Stephanie
Sawcer, Stephen
Arun, Tarunya
Pogreban, Tatiana
Brown, Terri-Louise
Begum, Thamanna
Antoine, Veronica
Rashid, Waqar
Noyce, Alastair J
Silber, Eli
Morris, Huw
Giovannoni, Gavin
Dobson, Ruth
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dfaa829aa3244981a9b0642497517dd8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfaa829aa3244981a9b0642497517dd8
Other Identifiers
ISSN
2044-6055
E-ISSN
2044-6055
DOI
10.1136/bmjopen-2023-071656
