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PAX8 and MECOM are interaction partners driving ovarian cancer

PAX8 and MECOM are interaction partners driving ovarian cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e459f346777c48fab385e6b2235f6c4c

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The transcription factor PAX8 is critical for the development of the thyroid and urogenital system. Comprehensive genomic screens furthermore indicate an additional oncogenic role for PAX8 in renal and ovarian cancers. While a plethora of PAX8-regulated genes in different contexts have been proposed, we still lack a mechanistic understanding of how...

Alternative Titles

Full title

PAX8 and MECOM are interaction partners driving ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e459f346777c48fab385e6b2235f6c4c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e459f346777c48fab385e6b2235f6c4c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22708-w

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