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17 results for Schmelzle,+Tobias

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ArticlesPeer ReviewedFull Text
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
Author / Creator:Stein, Claudia ; Bardet, Anaïs Flore ; Roma, Guglielmo ; Bergling, Sebastian ; Clay, Ieuan ; Ruchti, Alexandra ; Agarinis, Claudia ; Schmelzle, Tobias ; Bouwmeester, Tewis ; Schübeler, Dirk ; Bauer, Andreas
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-08, Vol.11 (8), p.e1005465
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Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
Author / Creator:Mesrouze, Yannick ; Bokhovchuk, Fedir ; Meyerhofer, Marco ; Fontana, Patrizia ; Zimmermann, Catherine ; Martin, Typhaine ; Delaunay, Clara ; Erdmann, Dirk ; Schmelzle, Tobias ; Chène, Patrick
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2017-04, Vol.6
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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens
Author / Creator:Barbosa, Inês A. M. ; Gopalakrishnan, Rajaraman ; Mercan, Samuele ; Mourikis, Thanos P. ; Martin, Typhaine ; Wengert, Simon ; Sheng, Caibin ; Ji, Fei ; Lopes, Rui ; Knehr, Judith ; Altorfer, Marc ; Lindeman, Alicia ; Russ, Carsten ; Naumann, Ulrike ; Golji, Javad ; Sprouffske, Kathleen ; Barys, Louise ; Tordella, Luca ; Schübeler, Dirk ; Schmelzle, Tobias ; Galli, Giorgio G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-07, Vol.14 (1), p.3907-15, Article 3907
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A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
Author / Creator:Mesrouze, Yannick ; Aguilar, Gustavo ; Bokhovchuk, Fedir ; Martin, Typhaine ; Delaunay, Clara ; Villard, Frédéric ; Meyerhofer, Marco ; Zimmermann, Catherine ; Fontana, Patrizia ; Wille, Roman ; Vorherr, Thomas ; Erdmann, Dirk ; Furet, Pascal ; Scheufler, Clemens ; Schmelzle, Tobias ; Affolter, Markus ; Chène, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.17442, Article 17442
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ArticlesPeer ReviewedFull Text
The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity
Author / Creator:Michaloglou, Chrysiis ; Lehmann, Waltraut ; Martin, Typhaine ; Delaunay, Clara ; Hueber, Andreas ; Barys, Louise ; Niu, Honglin ; Billy, Eric ; Wartmann, Markus ; Ito, Moriko ; Wilson, Christopher J. ; Digan, Mary Ellen ; Bauer, Andreas ; Voshol, Hans ; Christofori, Gerhard ; Sellers, William R. ; Hofmann, Francesco ; Schmelzle, Tobias
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e61916
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ArticlesPeer ReviewedFull Text
Correction of copy number induced false positives in CRISPR screens
Author / Creator:de Weck, Antoine ; Golji, Javad ; Jones, Michael D. ; Korn, Joshua M. ; Billy, Eric ; McDonald, E. Robert ; Schmelzle, Tobias ; Bitter, Hans ; Kauffmann, Audrey
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2018-07, Vol.14 (7), p.e1006279
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ArticlesPeer ReviewedFull Text
K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo
Author / Creator:Hofmann, Irmgard ; Weiss, Andreas ; Elain, Gaelle ; Schwaederle, Maria ; Sterker, Dario ; Romanet, Vincent ; Schmelzle, Tobias ; Lai, Albert ; Brachmann, Saskia M. ; Bentires-Alj, Mohamed ; Roberts, Thomas M. ; Sellers, William R. ; Hofmann, Francesco ; Maira, Sauveur-Michel
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-08, Vol.7 (8), p.e44146
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Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis
Author / Creator:Schmelzle, Tobias ; Mailleux, Arnaud A ; Overholtzer, Michael ; Carroll, Jason S ; Solimini, Nicole L ; Lightcap, Eric S ; Veiby, Ole P ; Brugge, Joan S
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.3787-3792
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ArticlesPeer ReviewedFull Text
Quantitation of Changes in Protein Phosphorylation: A Simple Method Based on Stable Isotope Labeling and Mass Spectrometry
Author / Creator:Bonenfant, Débora ; Schmelzle, Tobias ; Jacinto, Estela ; Crespo, José L. ; Mini, Thierry ; Hall, Michael N. ; Jenoe, Paul
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (3), p.880-885
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ArticlesPeer ReviewedFull Text
Engineering tumors with 3D scaffolds
Author / Creator:Fischbach, Claudia ; Chen, Ruth ; Matsumoto, Takuya ; Schmelzle, Tobias ; Brugge, Joan S ; Polverini, Peter J ; Mooney, David J
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2007-10, Vol.4 (10), p.855-860
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ArticlesPeer ReviewedFull Text
PAX8 and MECOM are interaction partners driving ovarian cancer
Author / Creator:Bleu, Melusine ; Mermet-Meillon, Fanny ; Apfel, Verena ; Barys, Louise ; Holzer, Laura ; Bachmann Salvy, Marianne ; Lopes, Rui ; Amorim Monteiro Barbosa, Inês ; Delmas, Cecile ; Hinniger, Alexandra ; Chau, Suzanne ; Kaufmann, Markus ; Haenni, Simon ; Berneiser, Karolin ; Wahle, Maria ; Moravec, Ivana ; Vissières, Alexandra ; Poetsch, Tania ; Ahrné, Erik ; Carte, Nathalie ; Voshol, Johannes ; Bechter, Elisabeth ; Hamon, Jacques ; Meyerhofer, Marco ; Erdmann, Dirk ; Fischer, Matteo ; Stachyra, Therese ; Freuler, Felix ; Gutmann, Sascha ; Fernández, César ; Schmelzle, Tobias ; Naumann, Ulrike ; Roma, Guglielmo ; Lawrenson, Kate ; Nieto-Oberhuber, Cristina ; Cobos-Correa, Amanda ; Ferretti, Stephane ; Schübeler, Dirk ; Galli, Giorgio Giacomo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-04, Vol.12 (1), p.2442-12, Article 2442
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ArticlesPeer ReviewedFull Text
Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers
Author / Creator:Chapeau, Emilie A. ; Sansregret, Laurent ; Galli, Giorgio G. ; Chène, Patrick ; Wartmann, Markus ; Mourikis, Thanos P. ; Jaaks, Patricia ; Baltschukat, Sabrina ; Barbosa, Ines A. M. ; Bauer, Daniel ; Brachmann, Saskia M. ; Delaunay, Clara ; Estadieu, Claire ; Faris, Jason E. ; Furet, Pascal ; Harlfinger, Stefanie ; Hueber, Andreas ; Jiménez Núñez, Eloísa ; Kodack, David P. ; Mandon, Emeline ; Martin, Typhaine ; Mesrouze, Yannick ; Romanet, Vincent ; Scheufler, Clemens ; Sellner, Holger ; Stamm, Christelle ; Sterker, Dario ; Tordella, Luca ; Hofmann, Francesco ; Soldermann, Nicolas ; Schmelzle, Tobias
Publisher:England: Nature Publishing Group
Journal title:Nature cancer, 2024-07, Vol.5 (7), p.1102-1120
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ArticlesPeer ReviewedFull Text
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers: e1005465
Author / Creator:Stein, Claudia ; Bardet, Anaïs Flore ; Roma, Guglielmo ; Bergling, Sebastian ; Clay, Ieuan ; Ruchti, Alexandra ; Agarinis, Claudia ; Schmelzle, Tobias ; Bouwmeester, Tewis ; Schübeler, Dirk ; Bauer, Andreas
Publisher:San Francisco: Public Library of Science
Journal title:PLoS genetics, 2015-08, Vol.11 (8)
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ArticlesPeer ReviewedFull Text
Author Correction: Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers
Author / Creator:Chapeau, Emilie A. ; Sansregret, Laurent ; Galli, Giorgio G. ; Chène, Patrick ; Wartmann, Markus ; Mourikis, Thanos P. ; Jaaks, Patricia ; Baltschukat, Sabrina ; Barbosa, Ines A. M. ; Bauer, Daniel ; Brachmann, Saskia M. ; Delaunay, Clara ; Estadieu, Claire ; Faris, Jason E. ; Furet, Pascal ; Harlfinger, Stefanie ; Hueber, Andreas ; Jiménez Núñez, Eloísa ; Kodack, David P. ; Mandon, Emeline ; Martin, Typhaine ; Mesrouze, Yannick ; Romanet, Vincent ; Scheufler, Clemens ; Sellner, Holger ; Stamm, Christelle ; Sterker, Dario ; Tordella, Luca ; Hofmann, Francesco ; Soldermann, Nicolas ; Schmelzle, Tobias
Publisher:England: Nature Publishing Group
Journal title:Nature cancer, 2024-07, Vol.5 (7), p.1130-1130
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ArticlesPeer ReviewedFull Text
Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast
Author / Creator:Friant, Sylvie ; Lombardi, Ruben ; Schmelzle, Tobias ; Hall, Michael N ; Riezman, Howard
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2001-12, Vol.20 (23), p.6783-6792
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ArticlesFull Text
A new perspective on the evolution of the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
Author / Creator:Mesrouze, Yannick ; Aguilar, Gustavo ; Bokhovchuk, Fedir ; Typhaine Martin ; Martin, Clara ; Villard, Frederic ; Meyerhofer, Marco ; Zimmermann, Catherine ; Fontana, Patrizia ; Wille, Roman ; Vorherr, Thomas ; Erdmann, Dirk ; Furet, Pascal ; Scheufler, Clemens ; Schmelzle, Tobias ; Affolter, Markus ; Chene, Patrick
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-05
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ArticlesFull Text
Correction of copy number induced false positives in CRISPR screens
Author / Creator:De Weck, Antoine ; Golji, Javad ; Jones, Michael D ; Korn, Joshua M ; Billy, Eric ; Mcdonald, E Robert ; Schmelzle, Tobias ; Bitter, Hans ; Kauffmann, Audrey
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2017-06
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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

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Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD

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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens

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A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors

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The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity

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Correction of copy number induced false positives in CRISPR screens

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K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

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Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

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Quantitation of Changes in Protein Phosphorylation: A Simple Method Based on Stable Isotope Labeling and Mass Spectrometry

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Engineering tumors with 3D scaffolds

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PAX8 and MECOM are interaction partners driving ovarian cancer

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Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers

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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers: e1005465

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Author Correction: Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers

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Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

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A new perspective on the evolution of the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors

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Correction of copy number induced false positives in CRISPR screens

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