Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection mo...
Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African trypanosomiasis
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and 'easy to use' oral drugs. Previously, we reported the discovery of the triazolopyrimidine (TP) class as selective kinetoplastid proteasome inhibitors with in vivo efficacy in...
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Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African trypanosomiasis
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TN_cdi_doaj_primary_oai_doaj_org_article_e5e1e471c0c746d79f9d7063a4a2f672
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5e1e471c0c746d79f9d7063a4a2f672
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ISSN
2414-6366
E-ISSN
2414-6366
DOI
10.3390/tropicalmed5010028
