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ArticlesPeer ReviewedFull Text
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
Author / Creator:Khare, Shilpi ; Nagle, Advait S. ; Biggart, Agnes ; Lai, Yin H. ; Liang, Fang ; Davis, Lauren C. ; Barnes, S. Whitney ; Mathison, Casey J. N. ; Myburgh, Elmarie ; Gao, Mu-Yun ; Gillespie, J. Robert ; Liu, Xianzhong ; Tan, Jocelyn L. ; Stinson, Monique ; Rivera, Ianne C. ; Ballard, Jaime ; Yeh, Vince ; Groessl, Todd ; Federe, Glenn ; Koh, Hazel X. Y. ; Venable, John D. ; Bursulaya, Badry ; Shapiro, Michael ; Mishra, Pranab K. ; Spraggon, Glen ; Brock, Ansgar ; Mottram, Jeremy C. ; Buckner, Frederick S. ; Rao, Srinivasa P. S. ; Wen, Ben G. ; Walker, John R. ; Tuntland, Tove ; Molteni, Valentina ; Glynne, Richard J. ; Supek, Frantisek
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-09, Vol.537 (7619), p.229-233
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ArticlesPeer ReviewedFull Text
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
Author / Creator:Plouffe, David ; Brinker, Achim ; McNamara, Case ; Henson, Kerstin ; Kato, Nobutaka ; Kuhen, Kelli ; Nagle, Advait ; Adrián, Francisco ; Matzen, Jason T ; Anderson, Paul ; Nam, Tae-gyu ; Gray, Nathanael S ; Chatterjee, Arnab ; Janes, Jeff ; Yan, S. Frank ; Trager, Richard ; Caldwell, Jeremy S ; Schultz, Peter G ; Zhou, Yingyao ; Winzeler, Elizabeth A
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (26), p.9059-9064
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Newsletter articlesFull Text
Chatterjee Arnab Kumar, Nagle Advait Suresh, Paraselli Prasuna, Kondreddi Ravinder Reddy, Leong Seh Yong, Mishra Pranab Kumar, Moreau Robert Joseph, Roland Jason Thomas, Sim Wei Lin Sandra, Simon Oliv...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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ArticlesPeer ReviewedFull Text
Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African trypanosomiasis
Author / Creator:Rao, Srinivasa P S ; Lakshminarayana, Suresh B ; Jiricek, Jan ; Kaiser, Marcel ; Ritchie, Ryan ; Myburgh, Elmarie ; Supek, Frantisek ; Tuntland, Tove ; Nagle, Advait ; Molteni, Valentina ; Mäser, Pascal ; Mottram, Jeremy C ; Barrett, Michael P ; Diagana, Thierry T
Publisher:Switzerland: MDPI AG
Journal title:Tropical medicine and infectious disease, 2020-03, Vol.5 (1), p.1-14
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ArticlesPeer ReviewedFull Text
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility
Author / Creator:Kato, Nobutaka ; Sakata, Tomoyo ; Breton, Ghislain ; Le Roch, Karine G ; Nagle, Advait ; Andersen, Carsten ; Bursulaya, Badry ; Henson, Kerstin ; Johnson, Jeffrey ; Kumar, Kota Arun ; Marr, Felix ; Mason, Daniel ; McNamara, Case ; Plouffe, David ; Ramachandran, Vandana ; Spooner, Muriel ; Tuntland, Tove ; Zhou, Yingyao ; Peters, Eric C ; Chatterjee, Arnab ; Schultz, Peter G ; Ward, Gary E ; Gray, Nathanael ; Harper, Jeffrey ; Winzeler, Elizabeth A
Journal title:Nature chemical biology, 2008-05, Vol.4 (6), p.347-356
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ArticlesPeer ReviewedFull Text
Targeting Plasmodium PI(4)K to eliminate malaria
Author / Creator:McNamara, Case W. ; Lee, Marcus C. S. ; Lim, Chek Shik ; Lim, Siau Hoi ; Roland, Jason ; Nagle, Advait ; Simon, Oliver ; Yeung, Bryan K. S. ; Chatterjee, Arnab K. ; McCormack, Susan L. ; Manary, Micah J. ; Zeeman, Anne-Marie ; Dechering, Koen J. ; Kumar, T. R. Santha ; Henrich, Philipp P. ; Gagaring, Kerstin ; Ibanez, Maureen ; Kato, Nobutaka ; Kuhen, Kelli L. ; Fischli, Christoph ; Rottmann, Matthias ; Plouffe, David M. ; Bursulaya, Badry ; Meister, Stephan ; Rameh, Lucia ; Trappe, Joerg ; Haasen, Dorothea ; Timmerman, Martijn ; Sauerwein, Robert W. ; Suwanarusk, Rossarin ; Russell, Bruce ; Renia, Laurent ; Nosten, Francois ; Tully, David C. ; Kocken, Clemens H. M. ; Glynne, Richard J. ; Bodenreider, Christophe ; Fidock, David A. ; Diagana, Thierry T. ; Winzeler, Elizabeth A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-12, Vol.504 (7479), p.248-253
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ArticlesPeer ReviewedFull Text
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
Author / Creator:Meister, Stephan ; Plouffe, David M. ; Kuhen, Kelli L. ; Bonamy, Ghislain M. C. ; Wu, Tao ; Barnes, S. Whitney ; Bopp, Selina E. ; Borboa, Rachel ; Bright, A. Taylor ; Che, Jianwei ; Cohen, Steve ; Dharia, Neekesh V. ; Gagaring, Kerstin ; Gettayacamin, Montip ; Gordon, Perry ; Groessl, Todd ; Kato, Nobutaka ; Lee, Marcus C. S. ; McNamara, Case W. ; Fidock, David A. ; Nagle, Advait ; Nam, Tae-gyu ; Richmond, Wendy ; Roland, Jason ; Rottmann, Matthias ; Zhou, Bin ; Froissard, Patrick ; Glynne, Richard J. ; Mazier, Dominique ; Sattabongkot, Jetsumon ; Schultz, Peter G. ; Tuntland, Tove ; Walker, John R. ; Zhou, Yingyao ; Chatterjee, Arnab ; Diagana, Thierry T. ; Winzeler, Elizabeth A.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2011-12, Vol.334 (6061), p.1372-1377
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ArticlesPeer ReviewedFull Text
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
Author / Creator:Vaidya, Akhil B. ; Morrisey, Joanne M. ; Zhang, Zhongsheng ; Das, Sudipta ; Daly, Thomas M. ; Otto, Thomas D. ; Spillman, Natalie J. ; Wyvratt, Matthew ; Siegl, Peter ; Marfurt, Jutta ; Wirjanata, Grennady ; Sebayang, Boni F. ; Price, Ric N. ; Chatterjee, Arnab ; Nagle, Advait ; Stasiak, Marcin ; Charman, Susan A. ; Angulo-Barturen, Iñigo ; Ferrer, Santiago ; Belén Jiménez-Díaz, María ; Martínez, María Santos ; Gamo, Francisco Javier ; Avery, Vicky M. ; Ruecker, Andrea ; Delves, Michael ; Kirk, Kiaran ; Berriman, Matthew ; Kortagere, Sandhya ; Burrows, Jeremy ; Fan, Erkang ; Bergman, Lawrence W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-11, Vol.5 (1), p.5521-5521, Article 5521
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ArticlesPeer ReviewedFull Text
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility
Author / Creator:Kato, Nobutaka ; Sakata, Tomoyo ; Breton, Ghislain ; Le Roch, Karine G ; Nagle, Advait ; Andersen, Carsten ; Bursulaya, Badry ; Henson, Kerstin ; Johnson, Jeffrey ; Kumar, Kota Arun ; Marr, Felix ; Mason, Daniel ; McNamara, Case ; Plouffe, David ; Ramachandran, Vandana ; Spooner, Muriel ; Tuntland, Tove ; Zhou, Yingyao ; Peters, Eric C ; Chatterjee, Arnab ; Schultz, Peter G ; Ward, Gary E ; Gray, Nathanael ; Harper, Jeffrey ; Winzeler, Elizabeth A
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2008-06, Vol.4 (6), p.347-356
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ArticlesPeer ReviewedFull Text
Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria
Author / Creator:McNamara, Case W ; Lee, Marcus CS ; Lim, Chek Shik ; Lim, Siau Hoi ; Roland, Jason ; Simon, Oliver ; Yeung, Bryan KS ; Chatterjee, Arnab K ; McCormack, Susan L ; Manary, Micah J ; Zeeman, Anne-Marie ; Dechering, Koen J ; Kumar, TR Santha ; Henrich, Philipp P ; Gagaring, Kerstin ; Ibanez, Maureen ; Kato, Nobutaka ; Kuhen, Kelli L ; Fischli, Christoph ; Nagle, Advait ; Rottmann, Matthias ; Plouffe, David M ; Bursulaya, Badry ; Meister, Stephan ; Rameh, Lucia ; Trappe, Joerg ; Haasen, Dorothea ; Timmerman, Martijn ; Sauerwein, Robert W ; Suwanarusk, Rossarin ; Russell, Bruce ; Renia, Laurent ; Nosten, Francois ; Tully, David C ; Kocken, Clemens HM ; Glynne, Richard J ; Bodenreider, Christophe ; Fidock, David A ; Diagana, Thierry T ; Winzeler, Elizabeth A
Journal title:Nature (London), 2013-11, Vol.504 (7479), p.248-253
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Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

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Chatterjee Arnab Kumar, Nagle Advait Suresh, Paraselli Prasuna, Kondreddi Ravinder Reddy, Leong Seh Yong, Mishra Pranab Kumar, Moreau Robert Joseph, Roland Jason Thomas, Sim Wei Lin Sandra, Simon Oliv...

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Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African trypanosomiasis

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Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility

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Targeting Plasmodium PI(4)K to eliminate malaria

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

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Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

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Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility

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Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

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