TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
About this item
Full title
Author / Creator
Rossitto, Moïra , Déjardin, Stephanie , Rands, Chris M. , Le Gras, Stephanie , Migale, Roberta , Rafiee, Mahmoud-Reza , Neirijnck, Yasmine , Pruvost, Alain , Nguyen, Anvi Laetitia , Bossis, Guillaume , Cammas, Florence , Le Gallic, Lionel , Wilhelm, Dagmar , Lovell-Badge, Robin , Boizet-Bonhoure, Brigitte , Nef, Serge and Poulat, Francis
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gonadal sexual fate in mammals is determined during embryonic development and must be actively maintained in adulthood. In the mouse ovary, oestrogen receptors and FOXL2 protect ovarian granulosa cells from transdifferentiation into Sertoli cells, their testicular counterpart. However, the mechanism underlying their protective effect is unknown. He...
Alternative Titles
Full title
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
Authors, Artists and Contributors
Author / Creator
Déjardin, Stephanie
Rands, Chris M.
Le Gras, Stephanie
Migale, Roberta
Rafiee, Mahmoud-Reza
Neirijnck, Yasmine
Pruvost, Alain
Nguyen, Anvi Laetitia
Bossis, Guillaume
Cammas, Florence
Le Gallic, Lionel
Wilhelm, Dagmar
Lovell-Badge, Robin
Boizet-Bonhoure, Brigitte
Nef, Serge
Poulat, Francis
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee83c64ad8d44323a3713a98d8b88a59
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee83c64ad8d44323a3713a98d8b88a59
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32061-1
