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Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and...

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd2d1ae1494471a8095c3f91f82dd1

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion

About this item

Full title

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion

Publisher

England: BioMed Central

Journal title

Cellular & molecular biology letters, 2024-07, Vol.29 (1), p.94-29, Article 94

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor formation in xenograft models. The molecular mechanisms by which loss of GJB3 leads to aneuploidy and cancer initiation and progression rema...

Alternative Titles

Full title

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f3dd2d1ae1494471a8095c3f91f82dd1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd2d1ae1494471a8095c3f91f82dd1

Other Identifiers

ISSN

1689-1392,1425-8153

E-ISSN

1689-1392

DOI

10.1186/s11658-024-00609-2

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