Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and...
Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion
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England: BioMed Central
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English
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England: BioMed Central
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We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor formation in xenograft models. The molecular mechanisms by which loss of GJB3 leads to aneuploidy and cancer initiation and progression rema...
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Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion
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TN_cdi_doaj_primary_oai_doaj_org_article_f3dd2d1ae1494471a8095c3f91f82dd1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dd2d1ae1494471a8095c3f91f82dd1
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1689-1392,1425-8153
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1689-1392
DOI
10.1186/s11658-024-00609-2